Breath-hold three-dimensional true-FISP imaging of coronary arteries using asymmetric sampling

Vibhas S. Deshpande, Steven M. Shea, Yiu Cho Chung, Richard M. McCarthy, J. Paul Finn, Debiao Li

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Purpose: To evaluate the feasibility of using asymmetric sampling in a three-dimensional, magnetization-prepared, segmented true-FISP (fast imaging with steady-state precession) sequence in order to reduce the sensitivity to resonance offsets, while simultaneously improving imaging speed. Materials and Methods: Asymmetric sampling reduces the repetition time, leading to reduced resonance offset effects and improved resolution in a fixed imaging time. However, it introduces additional phase terms due to blood flow, which can cause image artifacts. Computer simulations were performed to study the off-resonance and flow effects of asymmetric sampling in true-FISP. Coronary artery imaging was performed in healthy volunteers. Results: Simulations and volunteer studies show that image artifacts due to flow-induced phase variations may be acceptable at low velocities. Volunteer studies demonstrate that relatively high-resolution coronary artery images can then be acquired within a single breath-hold with segmented three-dimensional true-FISP imaging using data asymmetry in the readout direction. Conclusion: Asymmetric sampling is a useful modification to true-FISP for reducing the off-resonance artifacts and improving imaging speed when the flow velocities are small.

Original languageEnglish (US)
Pages (from-to)473-478
Number of pages6
JournalJournal of Magnetic Resonance Imaging
Issue number4
StatePublished - 2002
Externally publishedYes


  • Asymmetric sampling
  • Coronary arteries
  • Fast imaging
  • MR angiography
  • Magnetic resonance imaging
  • True-FISP

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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