Brain Protection in Cardiac Surgery

Kelly Grogan, Joshua Stearns, Charles W. Hogue

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


Brain injury is a major source of patient morbidity after cardiac surgery, and is associated with prolonged hospitalization, excessive operative mortality, high hospital costs, and altered quality of life. Frequency and the clinical manifestations depend on multiple factors, including the completeness and timing of neurologic testing. Ischemic brain infarctions may or may not be associated with stroke or postoperative neurocognitive dysfunction, but the long-term implications of these lesions on neurologic function have not yet been extensively evaluated. This article reviews the current views on the pathophysiologic basis of cerebral injury after cardiac surgery and provides a summary of measures aimed at reducing its occurrence.

Original languageEnglish (US)
Pages (from-to)521-538
Number of pages18
JournalAnesthesiology clinics
Issue number3
StatePublished - Sep 2008
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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