Brain and behavior changes during sleep deprivation

M. Thomas; H. Sing; G. Belenky; H. Holcomb; H. Mayberg; R. Dannals; H. Wagner; D. Thorne; K. Popp; L. Rowland; A. Welsh; D. Redmond

Brain and behavior changes during sleep deprivation

M. Thomas, H. Sing, G. Belenky, H. Holcomb, H. Mayberg, R. Dannals, H. Wagner, D. Thorne, K. Popp, L. Rowland, A. Welsh, D. Redmond

Research output: Contribution to journal › Conference article › peer-review

2 Scopus citations

Abstract

An experiment was conducted to demonstrate the degradation on cognitive performance and its brain correlates during sleep deprivation. The study used positron emission tomography (PET), a brain imaging technique, and 2-[¹⁸F]fluoro-2-deoxy-D-glucose (FDG), an index of regional cerebral glucose metabolic rate (rCMRglu) and brain activity. Twenty-four hours of sleep deprivation resulted in decreased alertness and cognitive performance, and in decreased rCMRglu, predominantly in prefrontal and posterior parietal cortices, and thalamus. These results provide evidence that the impairments produced by sleep deprivation have a biological basis in reduced brain activity in regions subserving higher-order cognitive and alertness functions.

Original language	English (US)
Number of pages	1
Journal	Proceedings of the Human Factors and Ergonomics Society
Volume	2
State	Published - Dec 1 1998
Externally published	Yes
Event	Proceedings of the 1998 42nd Annual Meeting 'Human Factors and Ergonomics Society' - Chicago, IL, USA Duration: Oct 5 1998 → Oct 9 1998

ASJC Scopus subject areas

Human Factors and Ergonomics

Cite this

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title = "Brain and behavior changes during sleep deprivation",

abstract = "An experiment was conducted to demonstrate the degradation on cognitive performance and its brain correlates during sleep deprivation. The study used positron emission tomography (PET), a brain imaging technique, and 2-[18F]fluoro-2-deoxy-D-glucose (FDG), an index of regional cerebral glucose metabolic rate (rCMRglu) and brain activity. Twenty-four hours of sleep deprivation resulted in decreased alertness and cognitive performance, and in decreased rCMRglu, predominantly in prefrontal and posterior parietal cortices, and thalamus. These results provide evidence that the impairments produced by sleep deprivation have a biological basis in reduced brain activity in regions subserving higher-order cognitive and alertness functions.",

author = "M. Thomas and H. Sing and G. Belenky and H. Holcomb and H. Mayberg and R. Dannals and H. Wagner and D. Thorne and K. Popp and L. Rowland and A. Welsh and D. Redmond",

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TY - JOUR

T1 - Brain and behavior changes during sleep deprivation

AU - Thomas, M.

AU - Sing, H.

AU - Belenky, G.

AU - Holcomb, H.

AU - Mayberg, H.

AU - Dannals, R.

AU - Wagner, H.

AU - Thorne, D.

AU - Popp, K.

AU - Rowland, L.

AU - Welsh, A.

AU - Redmond, D.

PY - 1998/12/1

Y1 - 1998/12/1

N2 - An experiment was conducted to demonstrate the degradation on cognitive performance and its brain correlates during sleep deprivation. The study used positron emission tomography (PET), a brain imaging technique, and 2-[18F]fluoro-2-deoxy-D-glucose (FDG), an index of regional cerebral glucose metabolic rate (rCMRglu) and brain activity. Twenty-four hours of sleep deprivation resulted in decreased alertness and cognitive performance, and in decreased rCMRglu, predominantly in prefrontal and posterior parietal cortices, and thalamus. These results provide evidence that the impairments produced by sleep deprivation have a biological basis in reduced brain activity in regions subserving higher-order cognitive and alertness functions.

AB - An experiment was conducted to demonstrate the degradation on cognitive performance and its brain correlates during sleep deprivation. The study used positron emission tomography (PET), a brain imaging technique, and 2-[18F]fluoro-2-deoxy-D-glucose (FDG), an index of regional cerebral glucose metabolic rate (rCMRglu) and brain activity. Twenty-four hours of sleep deprivation resulted in decreased alertness and cognitive performance, and in decreased rCMRglu, predominantly in prefrontal and posterior parietal cortices, and thalamus. These results provide evidence that the impairments produced by sleep deprivation have a biological basis in reduced brain activity in regions subserving higher-order cognitive and alertness functions.

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AN - SCOPUS:0032273309

SN - 1071-1813

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JO - Proceedings of the Human Factors and Ergonomics Society

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T2 - Proceedings of the 1998 42nd Annual Meeting 'Human Factors and Ergonomics Society'

Y2 - 5 October 1998 through 9 October 1998

ER -

Brain and behavior changes during sleep deprivation

Abstract

ASJC Scopus subject areas

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