Boston Keratoprosthesis type 1 (KPro) without contact lens wearing in end-stage corneal disease: The APEC experience

Guillermo De Wit-Carter, César Hernández-Chavarría, Pedro Ivan Navarro-Naranjo, Cristal Manzanillo-Rosario, Ricardo Navarro-Saucedo, Ana Mercedes García-Albisua, Everardo Hernandez-Quintela, Emmanuel Cabrera-Martínez, Gabriela Ordoñez-Ranz, Valeria Sanchez-Huerta

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To report the visual outcomes and survival analysis of keratoprosthesis without contact lens wearing in a tertiary eye care hospital in Mexico City, Asociación Para Evitar La Ceguera (APEC, Coyoacán, México). Design: Retrospective cohort with survival analysis Participants: Twenty-three eyes (22 patients) received KPro type 1 between 2015 and 2020 with a follow-up time of three years. Methods: We included analyzed data about past medical history, preoperative diagnosis, best-spectacle visual acuity (BSCVA), postoperative complications and retention rate. Univariate, bivariate and survival analysis were performed and reported. Results: The mean age was 58 ± 13.5 years (SD). 60.86% were male patients (14 eyes). Twelve-eyes (52%) achieved a BSCVA of 20/200 or better in the first and second year of follow-up. At 3 years, only 35% achieved 20/200 or better (BSCVA). Retention rate of Boston type 1 KPro was 87% (20 eyes) at 3 years follow-up. The most common complication was retroprosthetic membrane (RPM) which occurred in 9 eyes (39.1%), followed by corneal melting in 7 eyes (30.4%). Conclusions: We report the results of a retrospective cohort of twenty-three eyes (22 patients) who were implanted with a Boston type 1 KPro without contact lens wearing to treat corneal blindness. BSCVA improved significantly in most patients achieving 20/200 or better at the 2-year follow-up. Retention rate was 87%, with the presence of RPM as the most common complication.

Original languageEnglish (US)
JournalEuropean journal of ophthalmology
DOIs
StateAccepted/In press - 2023

Keywords

  • Boston KPro
  • RPM
  • Survival
  • contact lens
  • corneal blindness
  • extrusion
  • melting

ASJC Scopus subject areas

  • Ophthalmology

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