Border-cell migration: The race is on

Denise J. Montell

Research output: Contribution to journalReview articlepeer-review

224 Scopus citations


The conversion of stationary epithelial cells into migratory, invasive cells is important for normal embryonic development and tumour metastasis. Border-cell migration in the ovary of Drosophila melanogaster has emerged as a simple, genetically tractable model for studying this process. Three distinct signals, which are also upregulated in cancer, control border-cell migration, so identifying further genes that are involved in border-cell migration could provide new insights into tumour invasion.

Original languageEnglish (US)
Pages (from-to)13-24
Number of pages12
JournalNature Reviews Molecular Cell Biology
Issue number1
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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