Border-cell migration: The race is on

Denise J. Montell

doi:10.1038/nrm1006

Border-cell migration: The race is on

Denise J. Montell

School of Medicine

Research output: Contribution to journal › Review article › peer-review

224 Scopus citations

Abstract

The conversion of stationary epithelial cells into migratory, invasive cells is important for normal embryonic development and tumour metastasis. Border-cell migration in the ovary of Drosophila melanogaster has emerged as a simple, genetically tractable model for studying this process. Three distinct signals, which are also upregulated in cancer, control border-cell migration, so identifying further genes that are involved in border-cell migration could provide new insights into tumour invasion.

Original language	English (US)
Pages (from-to)	13-24
Number of pages	12
Journal	Nature Reviews Molecular Cell Biology
Volume	4
Issue number	1
DOIs	https://doi.org/10.1038/nrm1006
State	Published - Jan 1 2003

ASJC Scopus subject areas

Molecular Biology
Cell Biology

Access to Document

10.1038/nrm1006

Cite this

@article{c1b2c4106b564955b370654bc5b3dae5,

title = "Border-cell migration: The race is on",

abstract = "The conversion of stationary epithelial cells into migratory, invasive cells is important for normal embryonic development and tumour metastasis. Border-cell migration in the ovary of Drosophila melanogaster has emerged as a simple, genetically tractable model for studying this process. Three distinct signals, which are also upregulated in cancer, control border-cell migration, so identifying further genes that are involved in border-cell migration could provide new insights into tumour invasion.",

author = "Montell, {Denise J.}",

year = "2003",

month = jan,

day = "1",

doi = "10.1038/nrm1006",

language = "English (US)",

volume = "4",

pages = "13--24",

journal = "Nature Reviews Molecular Cell Biology",

issn = "1471-0072",

publisher = "Nature Publishing Group",

number = "1",

}

TY - JOUR

T1 - Border-cell migration

T2 - The race is on

AU - Montell, Denise J.

PY - 2003/1/1

Y1 - 2003/1/1

N2 - The conversion of stationary epithelial cells into migratory, invasive cells is important for normal embryonic development and tumour metastasis. Border-cell migration in the ovary of Drosophila melanogaster has emerged as a simple, genetically tractable model for studying this process. Three distinct signals, which are also upregulated in cancer, control border-cell migration, so identifying further genes that are involved in border-cell migration could provide new insights into tumour invasion.

AB - The conversion of stationary epithelial cells into migratory, invasive cells is important for normal embryonic development and tumour metastasis. Border-cell migration in the ovary of Drosophila melanogaster has emerged as a simple, genetically tractable model for studying this process. Three distinct signals, which are also upregulated in cancer, control border-cell migration, so identifying further genes that are involved in border-cell migration could provide new insights into tumour invasion.

UR - http://www.scopus.com/inward/record.url?scp=0037224378&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037224378&partnerID=8YFLogxK

U2 - 10.1038/nrm1006

DO - 10.1038/nrm1006

M3 - Review article

C2 - 12511865

AN - SCOPUS:0037224378

SN - 1471-0072

VL - 4

SP - 13

EP - 24

JO - Nature Reviews Molecular Cell Biology

JF - Nature Reviews Molecular Cell Biology

IS - 1

ER -

Border-cell migration: The race is on

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this