Bolus-chase peripheral 3D MRA using a dual-rate contrast media injection

Julianna M. Czum, Vincent B. Ho, Maureen N. Hood, Thomas K F Foo, Peter L. Choyke

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


In this pilot study, using a standard 40 mL gadolinium (Gd) chelate contrast dose, dual-rate (first 20 mL at 0.5 mL/sec; remaining 20 mL at 1.5 mL/sec) and fixed-rate (entire 40 mL dose at either 0.7 mL/sec or 2.0 mL/sec) injection schemes for multistation, bolus-chase magnetic resonance angiography (MRA) were compared in normal volunteers. Signal-to-noise ratio, contrast-to-noise ratio, and physician preference were determined for nine arterial segments. At the terminal station (calf), the dual-rate contrast injection improved arterial signal and contrast compared with both fixed-rate injection schemes and improved subjective vessel appearance compared with the 2.0 mL/sec, but not the 0.7 mL/sec, fixed-rate scheme. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish (US)
Pages (from-to)769-775
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Issue number5
StatePublished - 2000
Externally publishedYes


  • Arteries, extremities
  • Arteries, MR
  • Gadolinium
  • Magnetic resonance (MR), contrast agents
  • Magnetic resonance (MR), vascular studies
  • Magnetic resonance(MR), angiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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