Blood-flow velocities and their relationships in carotid and middle cerebral arteries

Yoji Nagai, Mary K. Kemper, Christopher J. Earley, E. Jeffrey Metter

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


This study defines normative flow velocity (FV) ranges for the common carotid (CCA), internal carotid (ICA) and middle cerebral arteries (MCA), compares them to subjects with nonfocal vascular disease (mild to moderate hypertension, diabetes, hyperlipidemia or coronary artery disease), and clarifies the association between carotid and MCA FVs. FVs were measured by carotid and transcranial Doppler ultrasonography in 278 healthy and 190 vascular-disease subjects. Normative FV ranges for CCA, ICA and MCA were large in healthy subjects, with modest gender and age differences. Vascular- disease subjects had similar FVs to healthy controls. MCA FVs were significantly correlated with carotid FVs (r ranged 0.26-0.50), but were only weakly or not significantly associated with them (β ranged 0.08-0.18) when controlling for age and gender. These findings suggest that normative FVs are not affected by the presence of nonfocal vascular disease, but carotid FVs do not aid in assessing MCA FVs.

Original languageEnglish (US)
Pages (from-to)1131-1136
Number of pages6
JournalUltrasound in Medicine and Biology
Issue number8
StatePublished - Oct 1998


  • Aging
  • Blood flow velocity
  • Carotid arteries
  • Cerebral arteries
  • Gender

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics


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