Bisphosphonates and Osteonecrosis: Potential Treatment or Serious Complication?

Robin N. Goytia; Andrew Salama; Harpal S. Khanuja

doi:10.1016/j.ocl.2008.12.002

Bisphosphonates and Osteonecrosis: Potential Treatment or Serious Complication?

Robin N. Goytia, Andrew Salama, Harpal S. Khanuja

School of Medicine

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

They are commonly used to treat osteoporosis and other diseases that involve osteoclast-mediated bone resorption, including Paget's disease and multiple myeloma. Their use in treating osteonecrosis of the femoral head has been studied and theoretically holds promise. There are complications associated with these medications, however, including the development of osteonecrosis in the jaw.

Original language	English (US)
Pages (from-to)	223-234
Number of pages	12
Journal	Orthopedic Clinics of North America
Volume	40
Issue number	2
DOIs	https://doi.org/10.1016/j.ocl.2008.12.002
State	Published - Apr 1 2009

Keywords

Avascular necrosis
BRONJ
Bisphosphonates
Osteonecrosis
Osteonecrosis of the femoral head
Osteonecrosis of the jaw

ASJC Scopus subject areas

Orthopedics and Sports Medicine

Access to Document

10.1016/j.ocl.2008.12.002

Cite this

@article{984fe05a5254443b889bd39c167f5e03,

title = "Bisphosphonates and Osteonecrosis: Potential Treatment or Serious Complication?",

abstract = "They are commonly used to treat osteoporosis and other diseases that involve osteoclast-mediated bone resorption, including Paget's disease and multiple myeloma. Their use in treating osteonecrosis of the femoral head has been studied and theoretically holds promise. There are complications associated with these medications, however, including the development of osteonecrosis in the jaw.",

keywords = "Avascular necrosis, BRONJ, Bisphosphonates, Osteonecrosis, Osteonecrosis of the femoral head, Osteonecrosis of the jaw",

author = "Goytia, {Robin N.} and Andrew Salama and Khanuja, {Harpal S.}",

year = "2009",

month = apr,

day = "1",

doi = "10.1016/j.ocl.2008.12.002",

language = "English (US)",

volume = "40",

pages = "223--234",

journal = "Orthopedic Clinics of North America",

issn = "0030-5898",

publisher = "W.B. Saunders",

number = "2",

}

TY - JOUR

T1 - Bisphosphonates and Osteonecrosis

T2 - Potential Treatment or Serious Complication?

AU - Goytia, Robin N.

AU - Salama, Andrew

AU - Khanuja, Harpal S.

PY - 2009/4/1

Y1 - 2009/4/1

N2 - They are commonly used to treat osteoporosis and other diseases that involve osteoclast-mediated bone resorption, including Paget's disease and multiple myeloma. Their use in treating osteonecrosis of the femoral head has been studied and theoretically holds promise. There are complications associated with these medications, however, including the development of osteonecrosis in the jaw.

AB - They are commonly used to treat osteoporosis and other diseases that involve osteoclast-mediated bone resorption, including Paget's disease and multiple myeloma. Their use in treating osteonecrosis of the femoral head has been studied and theoretically holds promise. There are complications associated with these medications, however, including the development of osteonecrosis in the jaw.

KW - Avascular necrosis

KW - BRONJ

KW - Bisphosphonates

KW - Osteonecrosis

KW - Osteonecrosis of the femoral head

KW - Osteonecrosis of the jaw

UR - http://www.scopus.com/inward/record.url?scp=63749092515&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=63749092515&partnerID=8YFLogxK

U2 - 10.1016/j.ocl.2008.12.002

DO - 10.1016/j.ocl.2008.12.002

M3 - Review article

C2 - 19358907

AN - SCOPUS:63749092515

SN - 0030-5898

VL - 40

SP - 223

EP - 234

JO - Orthopedic Clinics of North America

JF - Orthopedic Clinics of North America

IS - 2

ER -

Bisphosphonates and Osteonecrosis: Potential Treatment or Serious Complication?

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this