Biosynthesis of vitamin B12: Does 51-norcobyrinic acid or 151-norcobyrinic acid act as a precursor of cobyrinic acid?

Ingeborg Grgurina; Sheetal Handa; George Weaver; Philip A. Cole; Alan R. Battersby

doi:10.1039/C39900001514

Biosynthesis of vitamin B₁₂: Does 5¹-norcobyrinic acid or 15¹-norcobyrinic acid act as a precursor of cobyrinic acid?

Ingeborg Grgurina, Sheetal Handa, George Weaver, Philip A. Cole, Alan R. Battersby

School of Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

5¹-Norcobyrinic acid and 15¹-norcobyrinic acid are prepared in labelled form for enzymic experiments that show that neither one acts as a biosynthetic precursor of cobyrinic acid, a late intermediate en route to vitamin B₁₂.

Original language	English (US)
Pages (from-to)	1514-1516
Number of pages	3
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	21
DOIs	https://doi.org/10.1039/C39900001514
State	Published - Dec 1 1990

ASJC Scopus subject areas

Molecular Medicine

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title = "Biosynthesis of vitamin B12: Does 51-norcobyrinic acid or 151-norcobyrinic acid act as a precursor of cobyrinic acid?",

abstract = "51-Norcobyrinic acid and 151-norcobyrinic acid are prepared in labelled form for enzymic experiments that show that neither one acts as a biosynthetic precursor of cobyrinic acid, a late intermediate en route to vitamin B12.",

author = "Ingeborg Grgurina and Sheetal Handa and George Weaver and Cole, {Philip A.} and Battersby, {Alan R.}",

year = "1990",

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T2 - Does 51-norcobyrinic acid or 151-norcobyrinic acid act as a precursor of cobyrinic acid?

AU - Grgurina, Ingeborg

AU - Handa, Sheetal

AU - Weaver, George

AU - Cole, Philip A.

AU - Battersby, Alan R.

PY - 1990/12/1

Y1 - 1990/12/1

N2 - 51-Norcobyrinic acid and 151-norcobyrinic acid are prepared in labelled form for enzymic experiments that show that neither one acts as a biosynthetic precursor of cobyrinic acid, a late intermediate en route to vitamin B12.

AB - 51-Norcobyrinic acid and 151-norcobyrinic acid are prepared in labelled form for enzymic experiments that show that neither one acts as a biosynthetic precursor of cobyrinic acid, a late intermediate en route to vitamin B12.

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Biosynthesis of vitamin B₁₂: Does 5¹-norcobyrinic acid or 15¹-norcobyrinic acid act as a precursor of cobyrinic acid?

Abstract

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