TY - JOUR
T1 - Biostatistical Analysis of the Collaborative Glaucoma Study
T2 - I. Summary Report of the Risk Factors for Glaucomatous Visual-Field Defects
AU - Armaly, Mansour F.
AU - Krueger, Dean E.
AU - Maunder, Lucinda
AU - Becker, Bernard
AU - Hetherington, John
AU - Kolker, Allan E.
AU - Levene, Ralph Z.
AU - Maumenee, A. Edward
AU - Pollack, Irvin P.
AU - Shaffer, Robert N.
PY - 1980/12
Y1 - 1980/12
N2 - A prospective collaborative study was conducted in five centers during a 13-year period to identify factors that influence the development of visual-field defects (GVFDs) of open angle glaucoma. In 5,000 subjects, GVFDs developed in only 1.7% of eyes. Statistical analysis of 26 factors at first examination identified five that were significantly related to the development of GVFDs—outflow facility, age, applanation pressure, cup-disc ratio, and pressure change after water drinking. Their absolute initial value, and not its change with time, was the important predictor. Multivariate analysis showed their collective predictive power to be undesirably poor, indicating that other factors must play an important role in the development of GVFDs. Mortality-table analysis indicated that during a period of five years, 98.54% of eyes with initial pressure less than 20 mm Hg continued to be free from GVFDs as compared with 93.34% of those with pressure 20 mm Hg or greater.
AB - A prospective collaborative study was conducted in five centers during a 13-year period to identify factors that influence the development of visual-field defects (GVFDs) of open angle glaucoma. In 5,000 subjects, GVFDs developed in only 1.7% of eyes. Statistical analysis of 26 factors at first examination identified five that were significantly related to the development of GVFDs—outflow facility, age, applanation pressure, cup-disc ratio, and pressure change after water drinking. Their absolute initial value, and not its change with time, was the important predictor. Multivariate analysis showed their collective predictive power to be undesirably poor, indicating that other factors must play an important role in the development of GVFDs. Mortality-table analysis indicated that during a period of five years, 98.54% of eyes with initial pressure less than 20 mm Hg continued to be free from GVFDs as compared with 93.34% of those with pressure 20 mm Hg or greater.
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U2 - 10.1001/archopht.1980.01020041015002
DO - 10.1001/archopht.1980.01020041015002
M3 - Article
C2 - 7447768
AN - SCOPUS:0019123337
SN - 0003-9950
VL - 98
SP - 2163
EP - 2171
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 12
ER -