Biological screening of a unique drug library targeting MRGPRX2

Keyphrases

• Drug Library 100%
• Biological Screening 100%
• MRGPRX2 100%
• Hit Compound 40%
• G Protein-coupled Receptor 20%
• High-throughput Screening 20%
• Antineoplastic Agents 20%
• Non-allergic 20%
• Fluoroquinolones 20%
• Fluoroquinolone Antibiotics 20%
• Loss Function 10%
• Disease Groups 10%
• Opioids 10%
• Clinical Features 10%
• Single nucleotide Polymorphism 10%
• FDA-approved Drugs 10%
• Substance P 10%
• Degranulation 10%
• Mutagenesis 10%
• Bacitracin 10%
• Drug Class 10%
• Drug Target 10%
• Cellular Response 10%
• Assay System 10%
• Personalized Treatment 10%
• Daunorubicin 10%
• Antipsychotics 10%
• Structure-activity Relationship 10%
• Hydrochloride 10%
• Drug Candidates 10%
• Extracellular Signaling 10%
• Molecular Tools 10%
• Intervention Development 10%
• Tyrosine Kinase Inhibitor 10%
• Neuromuscular Blocking Agents 10%
• Pharmacogenetics 10%
• Calcium Response 10%
• Human Mast Cells 10%
• Imatinib Mesylate 10%
• Allergic Drug Reaction 10%
• Anti-allergic 10%
• Antihistaminic 10%
• Peptidergic 10%
• Pharmacologically Active 10%
• Chemical Classes 10%
• Drug Allergy 10%
• Function Properties 10%
• IgE-independent 10%
• Drug Indications 10%
• Anti-depression 10%
• Drug Hypersensitivity 10%
• Chlorpheniramine Maleate 10%
• Degranulation Assay 10%
• LAD2 10%
• Personalized Prevention 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Brompheniramine 33%