Bioassay for SF 86-327, a new antifungal agent

V. L. Kan, D. K. Henderson, J. E. Bennett

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


A bioassay with Trichophyton mentagrophytes is described for SF 86-327, an allylamine antifungal agent. SF 86-327 serum concentrations were measured by bioassay in 117 serum sampler from five patients receiving 500 mg/day. The peak, trough, and area under the concentration-time curve were determined after the first dose and at steady state. Drug accumulation occurred with prolonged therapy.

Original languageEnglish (US)
Pages (from-to)628-629
Number of pages2
JournalAntimicrobial agents and chemotherapy
Issue number4
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases


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