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Binding thermodynamics of statins to HMG-CoA reductase
Teresa Carbonell, Ernesto Freire
School of Medicine
Research output
:
Contribution to journal
›
Article
›
peer-review
79
Scopus citations
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Dive into the research topics of 'Binding thermodynamics of statins to HMG-CoA reductase'. Together they form a unique fingerprint.
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Keyphrases
Statins
100%
Binding Thermodynamics
100%
3-hydroxy-3-methylglutaryl-CoA Reductase
100%
Atorvastatin
50%
Binding Affinity
37%
Binding Enthalpy
37%
Cerivastatin
25%
Rosuvastatin
25%
Fluvastatin
25%
Prescription Drugs
12%
Cholesterol
12%
Clinical Significance
12%
Van Der Waals Interaction
12%
Kinetic Analysis
12%
Hydrogen Bonds (H-bonds)
12%
Inhibition Kinetics
12%
Enthalpy Change
12%
Thermodynamics
12%
Biosynthetic Pathway
12%
Isothermal Titration Calorimetry
12%
Interaction Type
12%
Inhibition Constant
12%
Entropy Change
12%
Hydrophobic Interaction
12%
Entropic Contribution
12%
Total Binding Energy
12%
Microcalorimetric Analysis
12%
Chemistry
Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor
100%
Pravastatin
25%
Fluvastatin
25%
Cerivastatin
25%