Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?

Hasan M. Shihab; Fred Lutwama; Theresa Piloya; Barbara Castelnuovo; Andrew D. Kambugu; Robert Colebunders

doi:10.3855/jidc.251

Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?

Hasan M. Shihab, Fred Lutwama, Theresa Piloya, Barbara Castelnuovo, Andrew D. Kambugu, Robert Colebunders

Research output: Contribution to journal › Article › peer-review

Abstract

A large number of patients are switched to second-line antiretroviral therapy, especially in resource limited settings. Lopinavir/Ritonavir is the main drug used in second-line treatment regimens. We describe a patient attending an HIV treatment centre in Kampala, Uganda, who presented with bilateral non-tender pitting inflammatory edema two weeks after switching to a Lopinavir/Ritonavir-containing second-line treatment regimen. The lack of an alternate explanation led us to suspect that Lopinavir/Ritonavir was potentially responsible for the edema.

Original language	English (US)
Pages (from-to)	405-407
Number of pages	3
Journal	Journal of infection in developing countries
Volume	3
Issue number	5
DOIs	https://doi.org/10.3855/jidc.251
State	Published - 2009
Externally published	Yes

Keywords

Edema
Lopinavir/Ritonavir
Resource-limited setting

ASJC Scopus subject areas

Parasitology
Microbiology
Infectious Diseases
Virology

Access to Document

10.3855/jidc.251

Cite this

@article{edf2a464bddc410fb942d677ce182466,

title = "Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?",

abstract = "A large number of patients are switched to second-line antiretroviral therapy, especially in resource limited settings. Lopinavir/Ritonavir is the main drug used in second-line treatment regimens. We describe a patient attending an HIV treatment centre in Kampala, Uganda, who presented with bilateral non-tender pitting inflammatory edema two weeks after switching to a Lopinavir/Ritonavir-containing second-line treatment regimen. The lack of an alternate explanation led us to suspect that Lopinavir/Ritonavir was potentially responsible for the edema.",

keywords = "Edema, Lopinavir/Ritonavir, Resource-limited setting",

author = "Shihab, {Hasan M.} and Fred Lutwama and Theresa Piloya and Barbara Castelnuovo and Kambugu, {Andrew D.} and Robert Colebunders",

year = "2009",

doi = "10.3855/jidc.251",

language = "English (US)",

volume = "3",

pages = "405--407",

journal = "Journal of infection in developing countries",

issn = "2036-6590",

publisher = "Journal of Infection in Developing Countries",

number = "5",

}

TY - JOUR

T1 - Bilateral pedal edema in an HIV patient

T2 - Lopinavir/Ritonavir-containing treatment regimen as a potential cause?

AU - Shihab, Hasan M.

AU - Lutwama, Fred

AU - Piloya, Theresa

AU - Castelnuovo, Barbara

AU - Kambugu, Andrew D.

AU - Colebunders, Robert

PY - 2009

Y1 - 2009

N2 - A large number of patients are switched to second-line antiretroviral therapy, especially in resource limited settings. Lopinavir/Ritonavir is the main drug used in second-line treatment regimens. We describe a patient attending an HIV treatment centre in Kampala, Uganda, who presented with bilateral non-tender pitting inflammatory edema two weeks after switching to a Lopinavir/Ritonavir-containing second-line treatment regimen. The lack of an alternate explanation led us to suspect that Lopinavir/Ritonavir was potentially responsible for the edema.

AB - A large number of patients are switched to second-line antiretroviral therapy, especially in resource limited settings. Lopinavir/Ritonavir is the main drug used in second-line treatment regimens. We describe a patient attending an HIV treatment centre in Kampala, Uganda, who presented with bilateral non-tender pitting inflammatory edema two weeks after switching to a Lopinavir/Ritonavir-containing second-line treatment regimen. The lack of an alternate explanation led us to suspect that Lopinavir/Ritonavir was potentially responsible for the edema.

KW - Edema

KW - Lopinavir/Ritonavir

KW - Resource-limited setting

UR - http://www.scopus.com/inward/record.url?scp=68049112213&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=68049112213&partnerID=8YFLogxK

U2 - 10.3855/jidc.251

DO - 10.3855/jidc.251

M3 - Article

C2 - 19759513

AN - SCOPUS:68049112213

SN - 2036-6590

VL - 3

SP - 405

EP - 407

JO - Journal of infection in developing countries

JF - Journal of infection in developing countries

IS - 5

ER -

Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this