TY - JOUR
T1 - Bilateral Facial Palsy Complicating Infectious Mononucleosis in Infancy
AU - Esumi, Noriko
AU - Machida, Yukiyasu
AU - Yoshioka, Hiroshi
AU - Sawada, Tadashi
AU - Kusimoki, Tomoichi
AU - Kasubuchi, Yasuo
PY - 1984/1
Y1 - 1984/1
N2 - This report presents the second case of infectious mononucleosis (IM) complicated fry facial palsy in Japan. The patient was an eight months old male infant. Diagnosis was defined as the Epstein-Barr virus (EBV) infection by analysis of EBV titer. Four days before admission the patient began to cough and became febrile. The next day he developed right facial palsy and on the third day left facial palsy. Cervical lymphadenopathy was noted, and the liver and the spleen were moderately enlarged. Neurological examination was negative except for bilateral facial palsy. The white blood cell count was 36,900; 57.5% lymphocytes, 16% atypical lymphocytes, and 5% monocytes. CSF revealed raised cell count ; 124/3 per μ I. Paul-Bunnel test was 1 : 128. Serum EBVCA-IgG titer rised from less than 1 5 to 1 I 80 in two weeks. From the eighth day steroid hormone preparations was administered to the patient for six days. Ten days after admission left facial palsy began to improve, and completely recovered six weeks later. About three months after the onset right facial palsy was completely recovered. Eighteen cases of facial palsy complicating IM have been reported in the literature. Ten of were bilateral. Most cases occurred in adolescence or in young adults, but in Japan two cases including the present case occurred in infancy. Neurological complications in IM including bilateral facial palsy sometimes appear as the sole manifestation of the illness. In infancy, moreover, EBV infection is often mild or atypical, so it is difficult to make the diagnosis. As one of the etiologies of facial palsy EBV should always be remembered.
AB - This report presents the second case of infectious mononucleosis (IM) complicated fry facial palsy in Japan. The patient was an eight months old male infant. Diagnosis was defined as the Epstein-Barr virus (EBV) infection by analysis of EBV titer. Four days before admission the patient began to cough and became febrile. The next day he developed right facial palsy and on the third day left facial palsy. Cervical lymphadenopathy was noted, and the liver and the spleen were moderately enlarged. Neurological examination was negative except for bilateral facial palsy. The white blood cell count was 36,900; 57.5% lymphocytes, 16% atypical lymphocytes, and 5% monocytes. CSF revealed raised cell count ; 124/3 per μ I. Paul-Bunnel test was 1 : 128. Serum EBVCA-IgG titer rised from less than 1 5 to 1 I 80 in two weeks. From the eighth day steroid hormone preparations was administered to the patient for six days. Ten days after admission left facial palsy began to improve, and completely recovered six weeks later. About three months after the onset right facial palsy was completely recovered. Eighteen cases of facial palsy complicating IM have been reported in the literature. Ten of were bilateral. Most cases occurred in adolescence or in young adults, but in Japan two cases including the present case occurred in infancy. Neurological complications in IM including bilateral facial palsy sometimes appear as the sole manifestation of the illness. In infancy, moreover, EBV infection is often mild or atypical, so it is difficult to make the diagnosis. As one of the etiologies of facial palsy EBV should always be remembered.
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U2 - 10.11251/ojjscn1969.16.301
DO - 10.11251/ojjscn1969.16.301
M3 - Article
C2 - 6487431
AN - SCOPUS:0021149159
SN - 0029-0831
VL - 16
SP - 301
EP - 308
JO - No To Hattatsu
JF - No To Hattatsu
IS - 4
ER -