Bilateral EK Rejection After COVID-19 Vaccine

Mya Abousy, Kelley Bohm, Christina Prescott, Jeanette M. Bonsack, Anisa Rowhani-Farid, Allen O. Eghrari

Research output: Contribution to journalArticlepeer-review


ABSTRACT: Owing to its rapid development, short-term and long-term effects of the COVID-19 vaccine are still not well understood. This case report highlights bilateral corneal endothelial graft rejection after administration of the Pfizer COVID-19 vaccine. A 73-year-old woman with bilateral Descemet stripping endothelial keratoplasty presented with bilateral decreased visual acuity, ocular pain, and photophobia after her second dose of the Pfizer-BioNTech COVID-19 vaccine. Two weeks after vaccine administration, the uncorrected visual acuity was 20/70 and 20/40. Central corneal thickness as measured by ultrasound was 809 and 825 μm and by Scheimfplug imaging was 788 and 751 μm at the pupil center. Slit-lamp biomicroscopy revealed quiet conjunctiva and sclera but was significant for thickened corneas with Descemet folds in both eyes. The patient was instructed to use prednisolone acetate 1% every 1 to 2 hours with Muro ointment at bedtime.

Original languageEnglish (US)
Pages (from-to)625-628
Number of pages4
JournalEye & contact lens
Issue number11
StatePublished - Nov 1 2021

ASJC Scopus subject areas

  • Ophthalmology


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