The massive amounts of β-aminoisobutyric acid (β-AIBA) in the urine of Burkitt’s lymphoma patients were measured along with other α-amino acids and β-alanine present in normal and decreased levels. The ratios of the amount of β-AIBA to β-alanine, in µmoles/kg urine collected in 24 hours, were elevated for all patients. The degree of elevation of β-AIBA excretion and the ratio of the two p-amino acids appeared to be related to the amount of tumor mass present. These analyses may have possible value in monitoring patients with Burkitt’s lymphoma during their disease course.
ASJC Scopus subject areas
- Cancer Research