Benefits and risks of emerging genetic technologies: The need for regulation

Research output: Contribution to journalArticlepeer-review

Abstract

Efforts to localize human genes to specific chromosomes and then to identify these genes and their role in specific diseases are increasing. These developments will expand the repertoire of genetic tests that are claimed to be predictive of future disease in the person being tested (presymptomatic tests) or in future offspring of those being tested (tests for reproductive options). In single-gene (mendelian) disorders, such tests may fail to detect all of the alleles capable of causing disease. In multifactorial disorders, positive results of tests for specific alleles will not always predict future disease because the other necessary factors may be absent. Policies are already in place to provide safe and effective clinical laboratory tests and interventions for subjects with positive test results, and to assure the quality of the laboratories performing such tests, but are not widely known or enforced for genetic tests.

Original languageEnglish (US)
Pages (from-to)1652-1657
Number of pages6
JournalClinical chemistry
Volume40
Issue number8
DOIs
StatePublished - 1994

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

Fingerprint

Dive into the research topics of 'Benefits and risks of emerging genetic technologies: The need for regulation'. Together they form a unique fingerprint.

Cite this