TY - CHAP
T1 - Basophils in Inflammation and Allergy Drug Design
AU - MacGlashan, Donald
PY - 2011/7/27
Y1 - 2011/7/27
KW - Basophil function modulation - receptors in basophils, inducing mediator release, inducing cytokine release
KW - Basophils and innate immune response - IgE-mediated response in basophils, the way cells can be stimulated to secrete mediators
KW - Basophils in inflammation - and allergy drug design, basophils versus mast cells
KW - Cytokine release, coincident - with degranulation and rapid
KW - Functionally active ligands (or their receptors) - on human basophils
KW - IL-3, regulating pre-Golgi pool of FcεRIα
KW - Mediators of inflammatory response - three classes of mediators, from basophils and metabolites of arachidonic acid
KW - Roles of basophils in immune response - classic primary immune response (T cells, B cells, and antigen-presenting cells [APCs])
KW - Syk expression, a weak correlation - with levels of Syk mRNA, regulating Syk in basophils
KW - Syk regulation on basophils - opportunity for selective manipulation
UR - http://www.scopus.com/inward/record.url?scp=84885566621&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84885566621&partnerID=8YFLogxK
U2 - 10.1002/9781444346688.ch9
DO - 10.1002/9781444346688.ch9
M3 - Chapter
AN - SCOPUS:84885566621
SN - 9781444330144
SP - 123
EP - 137
BT - Inflammation and Allergy Drug Design
PB - Wiley-Blackwell
ER -