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Basic science of mesenchymal stem cells in spine surgery

  • Hamid Hassanzadeh
  • , Islam Elboghdady
  • , Junyoung Ahn
  • , Kern Singh

Research output: Contribution to journalArticlepeer-review

Abstract

Current research is trending toward tissue engineering and regeneration of mesenchymal tissues in treatment of disease, particularly degenerative musculoskeletal pathology. Mesenchymal stem cells (MSCs) provide a potential option for improving bone and cartilage growth and repair based on their underlying potency. MSCs are attractive for their multipotent and immunological properties and ease of bulk manufacturing. This article reviews the basic science of MSCs and obstacles to clinical use and discusses the potential application in spinal surgery.

Original languageEnglish (US)
Pages (from-to)72-75
Number of pages4
JournalSeminars in Spine Surgery
Volume27
Issue number2
DOIs
StatePublished - Jun 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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