Core Messages: Basal cell carcinoma (BCC) is the most common human cancer. The most significant environmental carcinogen for BCC is ultraviolet light (UVL) exposure. Clinical pathological correlation is essential in choosing the appropriate treatment for the various subtypes of BCC. Untreated BCC or inappropriately managed BCC can cause significant morbidity and even mortality. The mainstay of treatment has focused on the total removal (excision) or mechanical destruction of the tumor. New treatment modalities include immune modulators, topical photodynamic therapy (PDT), and drugs targeting genetic defects. Education on skin cancer prevention should target all age groups.
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