Bacterial Endocarditis with a Tolerant Staphylococcal Organism

Julia A. McMillan; Leonard B. Weiner

doi:10.1177/000992288202100414

Bacterial Endocarditis with a Tolerant Staphylococcal Organism

Julia A. McMillan, Leonard B. Weiner

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

An eight-year-old boy developed staphylococcal endocarditis. He was treated initially with nafcillin and gentamicin, but he remained febrile. The minimum bactericidal concentration (MBC) of nafcillin was 130 times the minimum inhib itory concentration (MIC). Following the addition of rifampin to the antibiotic regimen, the patient became afebrile and recovered. The discrepancy between the MBC and MIC indicated tolerance to nafcillin. Tolerance is a mode of antibiotic resistance that must be considered in treating life-threatening illness.

Original language	English (US)
Pages (from-to)	252-254
Number of pages	3
Journal	Clinical pediatrics
Volume	21
Issue number	4
DOIs	https://doi.org/10.1177/000992288202100414
State	Published - Apr 1982
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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Bacterial Endocarditis with a Tolerant Staphylococcal Organism

Abstract

ASJC Scopus subject areas

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