Bacterial colonization of the tracheobronchial tree

R. A. Salata, J. J. Ellner

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Colonization of the tracheobronchial tree, especially with aerobic gram-negative bacteria, is a major and increasing problem in seriously ill and hospitalized patients. The association between colonization and nosocomial pneumonia is well established; pneumonia develops after aspiration of pathogens that have initially colonized the tracheobronchial tree. The same risk factors associated with hospital-acquired pneumonia are relevant for the development of colonization. An understanding of the pathogenesis of bacterial colonization is advancing rapidly and may provide the basis for strategies to diminish this significant problem.

Original languageEnglish (US)
Pages (from-to)623-633
Number of pages11
JournalClinics in Chest Medicine
Issue number4
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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