BACOM2.0 facilitates absolute normalization and quantification of somatic copy number alterations in heterogeneous tumor

Keyphrases

• Copy number 100%
• Heterogeneous Tumors 100%
• Somatic Copy number Alterations 100%
• Tumor Purity 100%
• Ovarian Cancer 33%
• Solid Tumors 33%
• Accuracy Improvement 33%
• Parameter Estimation 33%
• Cell Population 33%
• Simulated Dataset 33%
• Mixed Cell 33%
• Allele-specific 33%
• Quantification Method 33%
• Normalization Method 33%
• Ploidy 33%
• Aberrations 33%
• Cancer Dataset 33%
• Biological Context 33%
• Combined Outcome 33%
• Computational Approach 33%
• Tumor Stroma 33%
• Signal Parameters 33%
• Signal Normalization 33%
• Signal Mixing 33%
• Enhanced Functionality 33%

Earth and Planetary Sciences

• Parameter Estimation 100%
• Allele 100%
• Signal Mixing 100%

Biochemistry, Genetics and Molecular Biology

• Allele 100%
• Ploidy 100%