BACE1 is the major β-secretase for generation of Aβ peptides by neurons

Huaibin Cai; Yanshu Wang; Diane McCarthy; Hongjin Wen; David R. Borchelt; Donald L. Price; Philip C. Wong

doi:10.1038/85064

BACE1 is the major β-secretase for generation of Aβ peptides by neurons

Huaibin Cai, Yanshu Wang, Diane McCarthy, Hongjin Wen, David R. Borchelt, Donald L. Price, Philip C. Wong

School of Medicine

Research output: Contribution to journal › Article › peer-review

901 Scopus citations

Original language	English (US)
Pages (from-to)	233-234
Number of pages	2
Journal	Nature neuroscience
Volume	4
Issue number	3
DOIs	https://doi.org/10.1038/85064
State	Published - 2001

ASJC Scopus subject areas

Neuroscience(all)

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10.1038/85064

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@article{fe915874ca424797bf9478a132f53ef9,

title = "BACE1 is the major β-secretase for generation of Aβ peptides by neurons",

author = "Huaibin Cai and Yanshu Wang and Diane McCarthy and Hongjin Wen and Borchelt, {David R.} and Price, {Donald L.} and Wong, {Philip C.}",

note = "Funding Information: We thank S. Sisodia for CT15 antibodies, T. He, G. Cristostomo, V. Nehus and Y. Xu for technical support, and J. Nathans for reading the manuscript. This work was supported by NIH grant 1P01 AG14248, 2P50 AG05146, and by grants from the Adler Foundation and the Bristol-Myers Squibb Foundation. Copyright: Copyright 2007 Elsevier B.V., All rights reserved.",

year = "2001",

doi = "10.1038/85064",

language = "English (US)",

volume = "4",

pages = "233--234",

journal = "Nature Neuroscience",

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T1 - BACE1 is the major β-secretase for generation of Aβ peptides by neurons

AU - Cai, Huaibin

AU - Wang, Yanshu

AU - McCarthy, Diane

AU - Wen, Hongjin

AU - Borchelt, David R.

AU - Price, Donald L.

AU - Wong, Philip C.

N1 - Funding Information: We thank S. Sisodia for CT15 antibodies, T. He, G. Cristostomo, V. Nehus and Y. Xu for technical support, and J. Nathans for reading the manuscript. This work was supported by NIH grant 1P01 AG14248, 2P50 AG05146, and by grants from the Adler Foundation and the Bristol-Myers Squibb Foundation. Copyright: Copyright 2007 Elsevier B.V., All rights reserved.

PY - 2001

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U2 - 10.1038/85064

DO - 10.1038/85064

M3 - Article

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VL - 4

SP - 233

EP - 234

JO - Nature Neuroscience

JF - Nature Neuroscience

IS - 3

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BACE1 is the major β-secretase for generation of Aβ peptides by neurons

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