Avoiding DEET through insect gustatory receptors

Youngseok Lee; Sang Hoon Kim; Craig Montell

doi:10.1016/j.neuron.2010.07.006

Avoiding DEET through insect gustatory receptors

Youngseok Lee, Sang Hoon Kim, Craig Montell

School of Medicine

Research output: Contribution to journal › Article › peer-review

142 Scopus citations

Abstract

DEET is the most widely used insect repellent worldwide. In Drosophila olfactory receptor neurons (ORNs), DEET is detected through a mechanism employing the olfactory receptor, OR83b. However, it is controversial as to whether ORNs respond directly to DEET or whether DEET blocks the response to attractive odors. Here, we showed that DEET suppressed feeding behavior in Drosophila, and this effect was mediated by gustatory receptor neurons (GRNs). DEET was potent in suppressing feeding as

Original language	English (US)
Pages (from-to)	555-561
Number of pages	7
Journal	Neuron
Volume	67
Issue number	4
DOIs	https://doi.org/10.1016/j.neuron.2010.07.006
State	Published - 2010

Keywords

Molneuro
Signaling

ASJC Scopus subject areas

Neuroscience(all)
Medicine(all)

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10.1016/j.neuron.2010.07.006

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Avoiding DEET through insect gustatory receptors

Abstract

Keywords

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