Autism Spectrum Disorder Symptoms Among Children Enrolled in the Study to Explore Early Development (SEED)

Lisa D. Wiggins; Susan E. Levy; Julie Daniels; Laura Schieve; Lisa A. Croen; Carolyn DiGuiseppi; Lisa Blaskey; Ellen Giarelli; Li Ching Lee; Jennifer Pinto-Martin; Ann Reynolds; Catherine Rice; Cordelia Robinson Rosenberg; Patrick Thompson; Marshalyn Yeargin-Allsopp; Lisa Young; Diana Schendel

doi:10.1007/s10803-015-2476-8

Autism Spectrum Disorder Symptoms Among Children Enrolled in the Study to Explore Early Development (SEED)

Lisa D. Wiggins, Susan E. Levy, Julie Daniels, Laura Schieve, Lisa A. Croen, Carolyn DiGuiseppi, Lisa Blaskey, Ellen Giarelli, Li Ching Lee, Jennifer Pinto-Martin, Ann Reynolds, Catherine Rice, Cordelia Robinson Rosenberg, Patrick Thompson, Marshalyn Yeargin-Allsopp, Lisa Young, Diana Schendel

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

This study examined the phenotypic profiles of children aged 30–68 months in the Study to Explore Early Development (SEED). Children classified as autism spectrum disorder (ASD), developmental delay (DD) with ASD symptoms, DD without ASD symptoms, and population comparison (POP) differed significantly from each other on cognitive, adaptive, behavioral, and social functioning and the presence of parent-reported conditions. Children with ASD and DD with ASD symptoms had mild to severe ASD risk on several measures compared to children with other DD and POP who had little ASD risk across measures. We conclude that children in SEED have varying degrees of ASD impairment and associated deficits. SEED thus provides a valuable sample to explore ASD phenotypes and inform risk factor analyses.

Original language	English (US)
Pages (from-to)	3183-3194
Number of pages	12
Journal	Journal of Autism and Developmental Disorders
Volume	45
Issue number	10
DOIs	https://doi.org/10.1007/s10803-015-2476-8
State	Published - Oct 22 2015

Keywords

Autism
Etiology
Phenotype
Study to Explore Early Development
Symptoms

ASJC Scopus subject areas

Developmental and Educational Psychology

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10.1007/s10803-015-2476-8

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Wiggins, L. D., Levy, S. E., Daniels, J., Schieve, L., Croen, L. A., DiGuiseppi, C., Blaskey, L., Giarelli, E., Lee, L. C., Pinto-Martin, J., Reynolds, A., Rice, C., Rosenberg, C. R., Thompson, P., Yeargin-Allsopp, M., Young, L., & Schendel, D. (2015). Autism Spectrum Disorder Symptoms Among Children Enrolled in the Study to Explore Early Development (SEED). Journal of Autism and Developmental Disorders, 45(10), 3183-3194. https://doi.org/10.1007/s10803-015-2476-8

Wiggins, LD, Levy, SE, Daniels, J, Schieve, L, Croen, LA, DiGuiseppi, C, Blaskey, L, Giarelli, E, Lee, LC, Pinto-Martin, J, Reynolds, A, Rice, C, Rosenberg, CR, Thompson, P, Yeargin-Allsopp, M, Young, L & Schendel, D 2015, 'Autism Spectrum Disorder Symptoms Among Children Enrolled in the Study to Explore Early Development (SEED)', Journal of Autism and Developmental Disorders, vol. 45, no. 10, pp. 3183-3194. https://doi.org/10.1007/s10803-015-2476-8

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abstract = "This study examined the phenotypic profiles of children aged 30–68 months in the Study to Explore Early Development (SEED). Children classified as autism spectrum disorder (ASD), developmental delay (DD) with ASD symptoms, DD without ASD symptoms, and population comparison (POP) differed significantly from each other on cognitive, adaptive, behavioral, and social functioning and the presence of parent-reported conditions. Children with ASD and DD with ASD symptoms had mild to severe ASD risk on several measures compared to children with other DD and POP who had little ASD risk across measures. We conclude that children in SEED have varying degrees of ASD impairment and associated deficits. SEED thus provides a valuable sample to explore ASD phenotypes and inform risk factor analyses.",

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AU - Blaskey, Lisa

AU - Giarelli, Ellen

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AU - Pinto-Martin, Jennifer

AU - Reynolds, Ann

AU - Rice, Catherine

AU - Rosenberg, Cordelia Robinson

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Autism Spectrum Disorder Symptoms Among Children Enrolled in the Study to Explore Early Development (SEED)

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Keywords

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