Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein (Nature Communications, (2024), 15, 1, (4663), 10.1038/s41467-024-49016-3)

Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S. Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun LeeXiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J. Workman, Dario A.A. Vignali, Ulrike C. Muller, Cong Liu, Han Seok Ko, Valina L. Dawson, Ted M. Dawson

Research output: Contribution to journalComment/debatepeer-review

Abstract

The original version of this Article contained an error in Fig. 4, in which the statistical significance for conditions 410C9 versus Lag3−/− in panel 4i was reported as not significant when the association is significant. The correct version of Fig 4 is: (Figure presented.) Which replaces the previous incorrect version: (Figure presented.) The original version of this Article contained an error in the figure legend of Fig. 4 describing panels h and i, which incorrectly read ‘Anti-Lag3 410C9 (330 nM) reduced the internalization of α-syn-biotin PFF (1 μM) in WT neurons compared to Lag3–/– neurons. Quantification of the intensity of internalized α-syn-biotin PFF normalized by Rab7. (p-values: WT vs. Lag3−/− < 0.0001, mIgG vs. 410C9 < 0.0001, mIgG vs. Lag3−/− 0.0004, 410C9 vs. Lag3−/− 0.0641)’. The correct version replaces this with ‘Anti-Lag3 410C9 (330 nM) reduced the internalization of α-syn-biotin PFF (1 μM) in WT neurons compared to Lag3–/– neurons. Quantification of the intensity of internalized α-syn-biotin PFF normalized by Rab7. (p-values: WT vs. Lag3−/− < 0.0057, mIgG vs. 410C9 < 0.0277, 410C9 vs. Lag3−/− 0.0152).’ This has been corrected in both the PDF and HTML versions of the Article.

Original languageEnglish (US)
Article number6413
JournalNature communications
Volume15
Issue number1
DOIs
StatePublished - Dec 2024

ASJC Scopus subject areas

  • General Chemistry
  • General Biochemistry, Genetics and Molecular Biology
  • General Physics and Astronomy

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