Auer rod-like inclusions in a low-grade B-cell leukemia

Alexandra C. Hristov; Andrew Saladino; Victor E. Nava; Christopher D. Gocke

doi:10.1016/j.anndiagpath.2009.07.005

Auer rod-like inclusions in a low-grade B-cell leukemia

Alexandra C. Hristov
, Andrew Saladino
, Victor E. Nava
, Christopher D. Gocke

School of Medicine

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Auer rods define neoplastic blasts of myeloid origin. However, azurophilic, needle-shaped, Auer rod-like inclusions have rarely been reported in the neoplastic cells of patients with B-cell malignancies, including chronic lymphocytic leukemia/small lymphocytic lymphoma. Here, we report a case of low-grade B-cell leukemia most consistent with chronic lymphocytic leukemia/small lymphocytic lymphoma that displayed numerous intracytoplasmic, needle-shaped, azurophilic rods resembling Auer rods. Furthermore, we review the literature on Auer rod-like structures in B-cell neoplasms.

Original language	English (US)
Pages (from-to)	292-295
Number of pages	4
Journal	Annals of Diagnostic Pathology
Volume	14
Issue number	4
DOIs	https://doi.org/10.1016/j.anndiagpath.2009.07.005
State	Published - Aug 2010

Keywords

Auer rod-like inclusions
B-cell leukemia

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1016/j.anndiagpath.2009.07.005

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title = "Auer rod-like inclusions in a low-grade B-cell leukemia",

abstract = "Auer rods define neoplastic blasts of myeloid origin. However, azurophilic, needle-shaped, Auer rod-like inclusions have rarely been reported in the neoplastic cells of patients with B-cell malignancies, including chronic lymphocytic leukemia/small lymphocytic lymphoma. Here, we report a case of low-grade B-cell leukemia most consistent with chronic lymphocytic leukemia/small lymphocytic lymphoma that displayed numerous intracytoplasmic, needle-shaped, azurophilic rods resembling Auer rods. Furthermore, we review the literature on Auer rod-like structures in B-cell neoplasms.",

keywords = "Auer rod-like inclusions, B-cell leukemia",

author = "Hristov, \{Alexandra C.\} and Andrew Saladino and Nava, \{Victor E.\} and Gocke, \{Christopher D.\}",

year = "2010",

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doi = "10.1016/j.anndiagpath.2009.07.005",

language = "English (US)",

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AU - Hristov, Alexandra C.

AU - Saladino, Andrew

AU - Nava, Victor E.

AU - Gocke, Christopher D.

PY - 2010/8

Y1 - 2010/8

N2 - Auer rods define neoplastic blasts of myeloid origin. However, azurophilic, needle-shaped, Auer rod-like inclusions have rarely been reported in the neoplastic cells of patients with B-cell malignancies, including chronic lymphocytic leukemia/small lymphocytic lymphoma. Here, we report a case of low-grade B-cell leukemia most consistent with chronic lymphocytic leukemia/small lymphocytic lymphoma that displayed numerous intracytoplasmic, needle-shaped, azurophilic rods resembling Auer rods. Furthermore, we review the literature on Auer rod-like structures in B-cell neoplasms.

AB - Auer rods define neoplastic blasts of myeloid origin. However, azurophilic, needle-shaped, Auer rod-like inclusions have rarely been reported in the neoplastic cells of patients with B-cell malignancies, including chronic lymphocytic leukemia/small lymphocytic lymphoma. Here, we report a case of low-grade B-cell leukemia most consistent with chronic lymphocytic leukemia/small lymphocytic lymphoma that displayed numerous intracytoplasmic, needle-shaped, azurophilic rods resembling Auer rods. Furthermore, we review the literature on Auer rod-like structures in B-cell neoplasms.

KW - Auer rod-like inclusions

KW - B-cell leukemia

UR - https://www.scopus.com/pages/publications/77955665119

UR - https://www.scopus.com/pages/publications/77955665119#tab=citedBy

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DO - 10.1016/j.anndiagpath.2009.07.005

M3 - Article

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AN - SCOPUS:77955665119

SN - 1092-9134

VL - 14

SP - 292

EP - 295

JO - Annals of Diagnostic Pathology

JF - Annals of Diagnostic Pathology

IS - 4

ER -

Auer rod-like inclusions in a low-grade B-cell leukemia

Abstract

Keywords

ASJC Scopus subject areas

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