ATPASE-POSITIVE EPIDERMALE LANGERHANS-ZELLEN: HEMMUNG DER ATPASE DURCH AMMONIUM-BITUMINOSULFONAT (ICHTHYOL) UND PIX LITHANTHRACIS

W. Diezel; S. Gruner; G. J. Anhalt

ATPASE-POSITIVE EPIDERMALE LANGERHANS-ZELLEN: HEMMUNG DER ATPASE DURCH AMMONIUM-BITUMINOSULFONAT (ICHTHYOL) UND PIX LITHANTHRACIS

Translated title of the contribution: ATPase-positive epidermal Langerhans cells: Inhibition of the ATPase by ammonium bituminosulfonate (Ichthyol) and Pix lithanthracis

W. Diezel, S. Gruner, G. J. Anhalt

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Both ammonium bituminosulfonate (Ichthyol) and Pix lithanthracis reduce the number of ATPase-positive epidermal Langerhans cells (ELC) in the epidermis of BALB/c mice: vaselinum flavum alone vs vaselinum flavum + 5% Ichthyol: P < 0.01; vaselinum flavum vs vaselinum flavum + 5% Pix lithanthracis: P < 0.001. In contrast to this, the number of Ia-positive cells was not changed under identical conditions. These results allow the conclusion that Ichthyol and Pix lithanthracis are able to inhibit the enzyme ATPase on the surface of ELC. We infer that inhibition of ELC ATPase may be important in the regulation of ELC function (inhibition of cutaneous contact hypersensitivity).

Translated title of the contribution	ATPase-positive epidermal Langerhans cells: Inhibition of the ATPase by ammonium bituminosulfonate (Ichthyol) and Pix lithanthracis
Original language	German
Pages (from-to)	22-24
Number of pages	3
Journal	Hautarzt
Volume	43
Issue number	1
State	Published - Jan 1 1992
Externally published	Yes

Keywords

ATPase activity
Ichthyol
Langerhans cells
Pix lithanthracis

ASJC Scopus subject areas

Dermatology

Cite this

@article{bde35319a06c4323962bc78860d7b608,

title = "ATPASE-POSITIVE EPIDERMALE LANGERHANS-ZELLEN: HEMMUNG DER ATPASE DURCH AMMONIUM-BITUMINOSULFONAT (ICHTHYOL) UND PIX LITHANTHRACIS",

abstract = "Both ammonium bituminosulfonate (Ichthyol) and Pix lithanthracis reduce the number of ATPase-positive epidermal Langerhans cells (ELC) in the epidermis of BALB/c mice: vaselinum flavum alone vs vaselinum flavum + 5% Ichthyol: P < 0.01; vaselinum flavum vs vaselinum flavum + 5% Pix lithanthracis: P < 0.001. In contrast to this, the number of Ia-positive cells was not changed under identical conditions. These results allow the conclusion that Ichthyol and Pix lithanthracis are able to inhibit the enzyme ATPase on the surface of ELC. We infer that inhibition of ELC ATPase may be important in the regulation of ELC function (inhibition of cutaneous contact hypersensitivity).",

keywords = "ATPase activity, Ichthyol, Langerhans cells, Pix lithanthracis",

author = "W. Diezel and S. Gruner and Anhalt, {G. J.}",

year = "1992",

month = jan,

day = "1",

language = "German",

volume = "43",

pages = "22--24",

journal = "Hautarzt",

issn = "0017-8470",

publisher = "Springer Verlag",

number = "1",

}

TY - JOUR

T1 - ATPASE-POSITIVE EPIDERMALE LANGERHANS-ZELLEN

T2 - HEMMUNG DER ATPASE DURCH AMMONIUM-BITUMINOSULFONAT (ICHTHYOL) UND PIX LITHANTHRACIS

AU - Diezel, W.

AU - Gruner, S.

AU - Anhalt, G. J.

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Both ammonium bituminosulfonate (Ichthyol) and Pix lithanthracis reduce the number of ATPase-positive epidermal Langerhans cells (ELC) in the epidermis of BALB/c mice: vaselinum flavum alone vs vaselinum flavum + 5% Ichthyol: P < 0.01; vaselinum flavum vs vaselinum flavum + 5% Pix lithanthracis: P < 0.001. In contrast to this, the number of Ia-positive cells was not changed under identical conditions. These results allow the conclusion that Ichthyol and Pix lithanthracis are able to inhibit the enzyme ATPase on the surface of ELC. We infer that inhibition of ELC ATPase may be important in the regulation of ELC function (inhibition of cutaneous contact hypersensitivity).

AB - Both ammonium bituminosulfonate (Ichthyol) and Pix lithanthracis reduce the number of ATPase-positive epidermal Langerhans cells (ELC) in the epidermis of BALB/c mice: vaselinum flavum alone vs vaselinum flavum + 5% Ichthyol: P < 0.01; vaselinum flavum vs vaselinum flavum + 5% Pix lithanthracis: P < 0.001. In contrast to this, the number of Ia-positive cells was not changed under identical conditions. These results allow the conclusion that Ichthyol and Pix lithanthracis are able to inhibit the enzyme ATPase on the surface of ELC. We infer that inhibition of ELC ATPase may be important in the regulation of ELC function (inhibition of cutaneous contact hypersensitivity).

KW - ATPase activity

KW - Ichthyol

KW - Langerhans cells

KW - Pix lithanthracis

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M3 - Article

C2 - 1351891

AN - SCOPUS:0026570395

SN - 0017-8470

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JO - Hautarzt

JF - Hautarzt

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ATPASE-POSITIVE EPIDERMALE LANGERHANS-ZELLEN: HEMMUNG DER ATPASE DURCH AMMONIUM-BITUMINOSULFONAT (ICHTHYOL) UND PIX LITHANTHRACIS

Abstract

Keywords

ASJC Scopus subject areas

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