At-Risk Alcohol Use Among HIV-Positive Patients and the Completion of Patient-Reported Outcomes

For The Center For Aids Research Network Of Integrated Clinical Systems

doi:10.1007/s10461-017-1824-4

At-Risk Alcohol Use Among HIV-Positive Patients and the Completion of Patient-Reported Outcomes

For The Center For Aids Research Network Of Integrated Clinical Systems

Research output: Contribution to journal › Article › peer-review

Abstract

Heavy drinking is prevalent among people living with HIV. Studies use tools like patient-reported outcomes (PROs) to quantify alcohol use in a detailed, timely manner. However, if alcohol misuse influences PRO completion, selection bias may result. Our study included 14,145 adult HIV patients (133,036 visits) from CNICS who were eligible to complete PROs at an HIV primary care visit. We compared PRO completion proportions between patients with and without a clinical diagnosis of at-risk alcohol use in the prior year. We accounted for confounding by baseline and visit-specific covariates. PROs were completed at 20.8% of assessed visits. The adjusted difference in PRO completion proportions was −3.2% (95% CI −5.6 to −0.8%). The small association between receipt of an at-risk alcohol use diagnosis and decreased PRO completion suggests there could be modest selection bias in studies using the PRO alcohol measure.

Original language	English (US)
Pages (from-to)	1313-1322
Number of pages	10
Journal	AIDS and behavior
Volume	22
Issue number	4
DOIs	https://doi.org/10.1007/s10461-017-1824-4
State	Published - Apr 1 2018

Keywords

Alcohol consumption
HIV
PROs
Patient-reported outcomes
Selection bias

ASJC Scopus subject areas

Social Psychology
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1007/s10461-017-1824-4

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title = "At-Risk Alcohol Use Among HIV-Positive Patients and the Completion of Patient-Reported Outcomes",

abstract = "Heavy drinking is prevalent among people living with HIV. Studies use tools like patient-reported outcomes (PROs) to quantify alcohol use in a detailed, timely manner. However, if alcohol misuse influences PRO completion, selection bias may result. Our study included 14,145 adult HIV patients (133,036 visits) from CNICS who were eligible to complete PROs at an HIV primary care visit. We compared PRO completion proportions between patients with and without a clinical diagnosis of at-risk alcohol use in the prior year. We accounted for confounding by baseline and visit-specific covariates. PROs were completed at 20.8% of assessed visits. The adjusted difference in PRO completion proportions was −3.2% (95% CI −5.6 to −0.8%). The small association between receipt of an at-risk alcohol use diagnosis and decreased PRO completion suggests there could be modest selection bias in studies using the PRO alcohol measure.",

keywords = "Alcohol consumption, HIV, PROs, Patient-reported outcomes, Selection bias",

author = "{For The Center For Aids Research Network Of Integrated Clinical Systems} and Rudolph, {Jacqueline E.} and Cole, {Stephen R.} and Edwards, {Jessie K.} and Richard Moore and Conall O{\textquoteright}Cleirigh and Mathews, {Wm Christopher} and Katerina Christopoulos",

note = "Funding Information: This project was supported by Grant Numbers T32ES007018, R01AI100654, R24AI067039 and P30AI50410 from the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Dr. Stephen Cole and Dr. Jessie Edwards provided expert advice and consultation throughout the project process. The Center for AIDS Research Network of Integrated Clinical Systems supplied the data and information on the cohort and linked us to our CNICS collaborators, including Dr. Moore, Dr. O{\textquoteright}Cleirigh, Dr. Christopoulos, and Dr. Mathews. All authors declare that they have no conflicts of interest. Publisher Copyright: {\textcopyright} 2017, Springer Science+Business Media, LLC.",

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AU - Moore, Richard

AU - O’Cleirigh, Conall

AU - Mathews, Wm Christopher

AU - Christopoulos, Katerina

N1 - Funding Information: This project was supported by Grant Numbers T32ES007018, R01AI100654, R24AI067039 and P30AI50410 from the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Dr. Stephen Cole and Dr. Jessie Edwards provided expert advice and consultation throughout the project process. The Center for AIDS Research Network of Integrated Clinical Systems supplied the data and information on the cohort and linked us to our CNICS collaborators, including Dr. Moore, Dr. O’Cleirigh, Dr. Christopoulos, and Dr. Mathews. All authors declare that they have no conflicts of interest. Publisher Copyright: © 2017, Springer Science+Business Media, LLC.

PY - 2018/4/1

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N2 - Heavy drinking is prevalent among people living with HIV. Studies use tools like patient-reported outcomes (PROs) to quantify alcohol use in a detailed, timely manner. However, if alcohol misuse influences PRO completion, selection bias may result. Our study included 14,145 adult HIV patients (133,036 visits) from CNICS who were eligible to complete PROs at an HIV primary care visit. We compared PRO completion proportions between patients with and without a clinical diagnosis of at-risk alcohol use in the prior year. We accounted for confounding by baseline and visit-specific covariates. PROs were completed at 20.8% of assessed visits. The adjusted difference in PRO completion proportions was −3.2% (95% CI −5.6 to −0.8%). The small association between receipt of an at-risk alcohol use diagnosis and decreased PRO completion suggests there could be modest selection bias in studies using the PRO alcohol measure.

AB - Heavy drinking is prevalent among people living with HIV. Studies use tools like patient-reported outcomes (PROs) to quantify alcohol use in a detailed, timely manner. However, if alcohol misuse influences PRO completion, selection bias may result. Our study included 14,145 adult HIV patients (133,036 visits) from CNICS who were eligible to complete PROs at an HIV primary care visit. We compared PRO completion proportions between patients with and without a clinical diagnosis of at-risk alcohol use in the prior year. We accounted for confounding by baseline and visit-specific covariates. PROs were completed at 20.8% of assessed visits. The adjusted difference in PRO completion proportions was −3.2% (95% CI −5.6 to −0.8%). The small association between receipt of an at-risk alcohol use diagnosis and decreased PRO completion suggests there could be modest selection bias in studies using the PRO alcohol measure.

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At-Risk Alcohol Use Among HIV-Positive Patients and the Completion of Patient-Reported Outcomes

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Keywords

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