Abstract
Asymptotic confidence bands for generalized nonlinear regression models are developed. These are based on a combination of the S method of Scheffe, together with the delta method which is used to approximate the mean function by a linear combination of the parameters. The approach can be used in any situation where large sample theory can be applied to yield asymptotically normal estimates of the parameters, together with a consistent estimate of the large sample covariance matrix. Alternative formulations for various special cases allow the use of restricted range bands. A number of examples are given, including a pharmacokinetic model, a logit model with a background response rate, and a parametric survival model.
Original language | English (US) |
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Pages (from-to) | 142-150 |
Number of pages | 9 |
Journal | Biometrics |
Volume | 51 |
Issue number | 1 |
DOIs | |
State | Published - 1995 |
Externally published | Yes |
Keywords
- Asymptotic confidence bands
- Delta method
- Nonlinear regression models
- S method
ASJC Scopus subject areas
- Statistics and Probability
- General Biochemistry, Genetics and Molecular Biology
- General Immunology and Microbiology
- General Agricultural and Biological Sciences
- Applied Mathematics