Asymptomatic neurosyphilis after doxycycline therapy for early latent syphilis

Jonathan M. Zenilman, Steven Rand, Patricia Barditch, Anne M. Rompalo

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


A 50-year-old woman allergic to penicillin with early latent syphilis was treated with two courses of doxycycline. Ten months after diagnosis, she had no evidence of serologic response. A lumbar puncture demonstrated asymptomatic neurosyphilis. Penicillin desensitization was performed and she was successfully treated. This case re-emphasizes the need for close serologic follow-up in patients with Latent syphilis.

Original languageEnglish (US)
Pages (from-to)346-347
Number of pages2
JournalSexually transmitted diseases
Issue number6
StatePublished - 1993

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases


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