Abstract
PURPOSE: To report a case of conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma with presumed intraocular involvement. METHODS: Observational case report. RESULTS: A 73-year-old white man presented for a routine eye examination and was found to have a salmon-colored bulbar conjunctival mass of the left eye. Ultrasound showed a low-reflective mass with diffuse thickening of the ciliary body and choroid. Immunohistochemistry and flow cytometry of an incisional biopsy specimen suggested a polyclonal lesion. Treatment with topical steroids yielded no clinical improvement, and excisional biopsy was performed. A diagnosis of MALT lymphoma was made after polymerase chain reaction (PCR) analysis of the immunoglobulin heavy chain (IgH) locus revealed a clonal B-cell population. CONCLUSIONS: Conjunctival MALT lymphoma can present without symptoms and can extend intraocularly. PCR analysis of the IgH locus can identify lesion clonality when immunohistochemistry and flow cytometry fail to do so.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 484-486 |
| Number of pages | 3 |
| Journal | Cornea |
| Volume | 26 |
| Issue number | 4 |
| DOIs | |
| State | Published - May 2007 |
Keywords
- Conjunctiva
- Lymphoid hyperplasia
- Lymphoma
- Mucosaassociated lymphoid tissue
ASJC Scopus subject areas
- Ophthalmology