Association of parvovirus B19 with plasma cell-rich myocardial infiltrates after heart transplantation

Fritz E. Lower; Santosh Menon; Juan A. Sanchez

doi:10.1016/S1053-2498(01)00233-9

Association of parvovirus B19 with plasma cell-rich myocardial infiltrates after heart transplantation

Fritz E. Lower, Santosh Menon, Juan A. Sanchez

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

In this report we describe the development of plasma cell-rich myocardial infiltrates in association with a parvovirus B19 infection in a heart transplant patient. We hypothesize that the virus, either alone or in association with the cardiac allograft, may polarize the immune response in the direction of T helper 2 (Th2) cells rather than the expected Th1 cells. This favors the development of a humoral immune response and infiltration of the graft with plasma cells.

Original language	English (US)
Pages (from-to)	755-758
Number of pages	4
Journal	Journal of Heart and Lung Transplantation
Volume	20
Issue number	7
DOIs	https://doi.org/10.1016/S1053-2498(01)00233-9
State	Published - Jul 24 2001
Externally published	Yes

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine
Transplantation

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10.1016/S1053-2498(01)00233-9

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abstract = "In this report we describe the development of plasma cell-rich myocardial infiltrates in association with a parvovirus B19 infection in a heart transplant patient. We hypothesize that the virus, either alone or in association with the cardiac allograft, may polarize the immune response in the direction of T helper 2 (Th2) cells rather than the expected Th1 cells. This favors the development of a humoral immune response and infiltration of the graft with plasma cells.",

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AU - Menon, Santosh

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AB - In this report we describe the development of plasma cell-rich myocardial infiltrates in association with a parvovirus B19 infection in a heart transplant patient. We hypothesize that the virus, either alone or in association with the cardiac allograft, may polarize the immune response in the direction of T helper 2 (Th2) cells rather than the expected Th1 cells. This favors the development of a humoral immune response and infiltration of the graft with plasma cells.

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Association of parvovirus B19 with plasma cell-rich myocardial infiltrates after heart transplantation

Abstract

ASJC Scopus subject areas

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