TY - JOUR
T1 - Association of hepatitis C virus infection with sexual exposure in southern India
AU - Marx, Melissa A.
AU - Murugavel, K. G.
AU - Tarwater, Patrick M.
AU - SriKrishnan, A. K.
AU - Thomas, David L.
AU - Solomon, Suniti
AU - Celentano, David D.
N1 - Funding Information:
Financial support: National Institute of Mental Health (collaborative grant U10-MH61543) and Fogarty New and Minority Investigator’s Award.
PY - 2003/8/15
Y1 - 2003/8/15
N2 - To determine the association between sexual exposure and hepatitis C virus (HCV) infection in urban Chennai, India, a random sample of adults who live in a slum community completed interviews and provided samples to test for HCV, herpes simplex virus type 2 (HSV-2), and other sexually transmitted infections (STIs). All analyses excluded recent and current injection drug users. HCV infection was not associated with the reported number of sex partners for men or women. Women were more likely to be HCV infected if they reported previous genital ulcer disease (adjusted odds ratio [AOR], 3.88; 95% confidence interval [95% CI], 0.94-16.0; marginally statistically significant). Men were more likely to be HCV infected if they were HSV-2 infected (AOR, 3.85; 95% CI, 1.18-12.6) or reported having had sex with men (AOR, 3.61; 95% CI, 1.00-13.1). Sexual transmission of HCV infection may be facilitated by ulcerative STIs and male-male sexual practices, but it appears to occur infrequently in this population.
AB - To determine the association between sexual exposure and hepatitis C virus (HCV) infection in urban Chennai, India, a random sample of adults who live in a slum community completed interviews and provided samples to test for HCV, herpes simplex virus type 2 (HSV-2), and other sexually transmitted infections (STIs). All analyses excluded recent and current injection drug users. HCV infection was not associated with the reported number of sex partners for men or women. Women were more likely to be HCV infected if they reported previous genital ulcer disease (adjusted odds ratio [AOR], 3.88; 95% confidence interval [95% CI], 0.94-16.0; marginally statistically significant). Men were more likely to be HCV infected if they were HSV-2 infected (AOR, 3.85; 95% CI, 1.18-12.6) or reported having had sex with men (AOR, 3.61; 95% CI, 1.00-13.1). Sexual transmission of HCV infection may be facilitated by ulcerative STIs and male-male sexual practices, but it appears to occur infrequently in this population.
UR - http://www.scopus.com/inward/record.url?scp=0042442481&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0042442481&partnerID=8YFLogxK
U2 - 10.1086/376639
DO - 10.1086/376639
M3 - Article
C2 - 12905135
AN - SCOPUS:0042442481
SN - 1058-4838
VL - 37
SP - 514
EP - 520
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 4
ER -