@article{afb1e37d5b6d459382ed6385ba1f0c03,
title = "Association of Eating and Sleeping Intervals With Weight Change Over Time: The Daily24 Cohort",
abstract = "BACKGROUND: We aim to evaluate the association between meal intervals and weight trajectory among adults from a clinical cohort. METHODS AND RESULTS: This is a multisite prospective cohort study of adults recruited from 3 health systems. Over the 6-month study period, 547 participants downloaded and used a mobile application to record the timing of meals and sleep for at least 1 day. We obtained information on weight and comorbidities at each outpatient visit from electronic health records for up to 10 years before until 10 months after baseline. We used mixed linear regression to model weight trajectories. Mean age was 51.1 (SD 15.0) years, and body mass index was 30.8 (SD 7.8) kg/m2; 77.9% were women, and 77.5% reported White race. Mean interval from first to last meal was 11.5 (2.3) hours and was not associated with weight change. The number of meals per day was positively associated with weight change. The average difference in annual weight change (95% CI) associated with an increase of 1 daily meal was 0.28 kg (0.02–0.53). CONCLUSIONS: Number of daily meals was positively associated with weight change over 6 years. Our findings did not support the use of time-restricted eating as a strategy for long-term weight loss in a general medical population.",
keywords = "eating behavior, eating intervals, weight trajectory",
author = "Di Zhao and Eliseo Guallar and Woolf, {Thomas B.} and Lindsay Martin and Harold Lehmann and Janelle Coughlin and Katherine Holzhauer and Goheer, {Attia A.} and McTigue, {Kathleen M.} and Lent, {Michelle R.} and Marquis Hawkins and Clark, {Jeanne M.} and Bennett, {Wendy L.}",
note = "Funding Information: This research was funded by the American Heart Association, Strategically Funded Research Network (SFRN) Grant # 17SFRN33560006 to Johns Hopkins University School of Medicine. The authors also acknowledge assistance for clinical data coordination and retrieval from the Core for Clinical Research Data Acquisition, supported in part by the Johns Hopkins Institute for Clinical and Translational Research (UL1TR001079). The research reported in this publication was conducted, in part, using PCORnet{\textregistered}, the National Patient-Centered Clinical Research Network. PCORnet{\textregistered} has been developed with funding from the Patient-Centered Outcomes Research Institute{\textregistered} (PCORI{\textregistered}). The PaTH Clinical Research Network{\textquoteright}s participation in PCORnet{\textregistered} was funded through PCORI{\textregistered} Award (CDRN-1306-04912). Funding Information: Outside of this work, Dr Clark served as a scientific advisor for NovoNordisk and Boehringer Ingelheim. Dr Woolf helped found DaiWare, which developed the software under a service contract with Johns Hopkins University and with funding from the American Heart Association. There are no current plans to commercialize the Daily24 app used in this project, and this project was not initiated with any funds from DaiWare. None of the other authors report any disclosures. Publisher Copyright: {\textcopyright} 2023 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.",
year = "2023",
month = feb,
day = "7",
doi = "10.1161/JAHA.122.026484",
language = "English (US)",
volume = "12",
journal = "Journal of the American Heart Association",
issn = "2047-9980",
publisher = "Wiley-Blackwell",
number = "3",
}