Assignment of the haemophilia B (Factor IX) locus to the q26‐qter region of the X chromosome

Y. BOYD; V. J. BUCKLE; E. A. MUNRO; K. H. CHOO; B. R. MIGEON; I. W. CRAIG

doi:10.1111/j.1469-1809.1984.tb01009.x

Assignment of the haemophilia B (Factor IX) locus to the q26‐qter region of the X chromosome

Y. BOYD
, V. J. BUCKLE
, E. A. MUNRO
, K. H. CHOO
, B. R. MIGEON
, I. W. CRAIG

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Two independent approaches have provided an assignment for the factor IX (Haemophilia B) locus to Xq26–qter, the distal region of the X chromosome long arm. Cloned DNA sequences of the gene were hybridized to restriction enzyme digests of DNA prepared from a series of somatic cell hybrids containing different X‐chromosomal regions and also in situ to prepared metaphase chromosomes.

Original language	English (US)
Pages (from-to)	145-152
Number of pages	8
Journal	Annals of Human Genetics
Volume	48
Issue number	2
DOIs	https://doi.org/10.1111/j.1469-1809.1984.tb01009.x
State	Published - May 1984
Externally published	Yes

ASJC Scopus subject areas

Genetics
Genetics(clinical)

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10.1111/j.1469-1809.1984.tb01009.x

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abstract = "Two independent approaches have provided an assignment for the factor IX (Haemophilia B) locus to Xq26–qter, the distal region of the X chromosome long arm. Cloned DNA sequences of the gene were hybridized to restriction enzyme digests of DNA prepared from a series of somatic cell hybrids containing different X‐chromosomal regions and also in situ to prepared metaphase chromosomes.",

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AU - BOYD, Y.

AU - BUCKLE, V. J.

AU - MUNRO, E. A.

AU - CHOO, K. H.

AU - MIGEON, B. R.

AU - CRAIG, I. W.

PY - 1984/5

Y1 - 1984/5

N2 - Two independent approaches have provided an assignment for the factor IX (Haemophilia B) locus to Xq26–qter, the distal region of the X chromosome long arm. Cloned DNA sequences of the gene were hybridized to restriction enzyme digests of DNA prepared from a series of somatic cell hybrids containing different X‐chromosomal regions and also in situ to prepared metaphase chromosomes.

AB - Two independent approaches have provided an assignment for the factor IX (Haemophilia B) locus to Xq26–qter, the distal region of the X chromosome long arm. Cloned DNA sequences of the gene were hybridized to restriction enzyme digests of DNA prepared from a series of somatic cell hybrids containing different X‐chromosomal regions and also in situ to prepared metaphase chromosomes.

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Assignment of the haemophilia B (Factor IX) locus to the q26‐qter region of the X chromosome

Abstract

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