Evaluación del impacto económico de la vacuna antirrotavírica en Venezuela

Translated title of the contribution: Assessment of the economic impact of the antiretroviral vaccine in Venezuela

Dagna Constenla, Irene Pérez-Schael, Richard D. Rheingans, Lynn Antil, Hans Salas, Juan Pablo Yarzábal

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Objective. To assess the cost of medical care for rotavirus gastroenteritis and the cost-effectiveness of the antiretroviral vaccine in Venezuelan children under five. Methods. We used an economic model that comprises epidemiologic information, vaccine efficacy, and the cost of medical care in connection with rotavirus gastroenteritis, viewed from a social perspective. In order to determine the effectiveness of the vaccine, we estimated the number of hospitalized cases, of medical visits, and of deaths averted after vaccination. The cost-effectiveness of the vaccine was determined on the basis of the number of disability-adjusted life years (DALYs) and cases averted. Results. In Venezuela, health services spend approximately US$ 4.2 million yearly on covering the costs of medical care for rotavirus-related disease. In a vaccinated cohort, an antiretroviral vaccination program would prevent around 52% (186) of the deaths, 54% (7 232) of the hospitalizations, and 50% (55 168) of the ambulatory visits that take place during the first five years of life. For an estimated cost of approximately US$ 24 per individual vaccination schedule, the cost-effectiveness ratio obtained is US$ 1 352 per DALY. Conclusions. The results of this study suggest that antiretroviral vaccination is a cost-effective strategy for preventing rotavirus gastroenteritis in Venezuela, since it can prevent deaths and DALYs in the population under five years of age.

Translated title of the contributionAssessment of the economic impact of the antiretroviral vaccine in Venezuela
Original languageSpanish
Pages (from-to)213-222
Number of pages10
JournalRevista Panamericana de Salud Publica/Pan American Journal of Public Health
Issue number4
StatePublished - Oct 2006
Externally publishedYes


  • Cost-effectiveness evaluation
  • Gastroenteritis
  • Prevention
  • Rotavirus
  • Vaccination
  • Venezuela

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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