TY - JOUR
T1 - Assessment of glycemia in diabetes mellitus
T2 - Hemoglobin A1c
AU - Saudek, C. D.
AU - Kalyani, Rita R.
AU - Derr, R. L.
PY - 2005/4/1
Y1 - 2005/4/1
N2 - The monitoring of glycemia is an essential component of diabetes care. It may be divided into self-monitoring of blood glucose (SMBG), which measures the immediate level of glycemia, and measurement of hemoglobin A1c (HbA1c), which reflects longer-term glycemia. SMBG was discussed in an earlier review. HbA1c is a measure of erythrocyte hemoglobin glycation, and since erythrocytes have about a 120 day life span, HbA 1c reflects mean glycemia for the previous 3 months (weighted to the most recent month). There are several conditions that confound the HbA 1c measurement such as hemolytic anaemia (lowers HbA1c) or aplastic anaemia (raises it), but in most circumstances HbA1c is a valid index of glycemia. The recommendation is to measure HbA1c every 3-6 months, and treat to a target level of <7%. If these recommendations were successfully followed in most people with diabetes, long-term complications, especially microvascular complications, would be markedly reduced.
AB - The monitoring of glycemia is an essential component of diabetes care. It may be divided into self-monitoring of blood glucose (SMBG), which measures the immediate level of glycemia, and measurement of hemoglobin A1c (HbA1c), which reflects longer-term glycemia. SMBG was discussed in an earlier review. HbA1c is a measure of erythrocyte hemoglobin glycation, and since erythrocytes have about a 120 day life span, HbA 1c reflects mean glycemia for the previous 3 months (weighted to the most recent month). There are several conditions that confound the HbA 1c measurement such as hemolytic anaemia (lowers HbA1c) or aplastic anaemia (raises it), but in most circumstances HbA1c is a valid index of glycemia. The recommendation is to measure HbA1c every 3-6 months, and treat to a target level of <7%. If these recommendations were successfully followed in most people with diabetes, long-term complications, especially microvascular complications, would be markedly reduced.
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M3 - Review article
C2 - 15987016
AN - SCOPUS:23044509686
SN - 0004-5772
VL - 53
SP - 299
EP - 305
JO - Journal of Association of Physicians of India
JF - Journal of Association of Physicians of India
IS - APR
ER -