Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes

Scott J. Cameron; Gary B. Green; C. Nicole White; Omar F. Laterza; William Clarke; Hong Kim; Lori J. Sokoll

doi:10.1016/j.clinbiochem.2005.10.011

Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes

Scott J. Cameron, Gary B. Green, C. Nicole White, Omar F. Laterza, William Clarke, Hong Kim, Lori J. Sokoll

School of Medicine

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Objectives: The relationship between BNP and NT-proBNP among physiologically and clinically relevant demographic subgroups has never been clarified in the context of the emergency department (ED). Design and methods: A blood sample taken from patients presenting to the E.D. with suspected acute coronary syndromes (ACS) was analyzed for BNP and NT-proBNP, and correlation between them was examined as an entire group then as subgroups according to gender, ethnicity, age, and comorbidity variables. Results: BNP and NT-proBNP correlate well (0.89, P < 0.0001) in a population of 420 patients and in patient subgroups with a history of various etiologies, including vascular disorders. Conclusions: In general, BNP and NT-proBNP correlate very well in patients with suspected ACS and may aid in the risk stratification process in emergency departments.

Original language	English (US)
Pages (from-to)	11-18
Number of pages	8
Journal	Clinical Biochemistry
Volume	39
Issue number	1
DOIs	https://doi.org/10.1016/j.clinbiochem.2005.10.011
State	Published - Jan 2006

Keywords

BNP
Chest pain
Correlation
Emergency department
NT-proBNP

ASJC Scopus subject areas

Clinical Biochemistry

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10.1016/j.clinbiochem.2005.10.011

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title = "Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes",

abstract = "Objectives: The relationship between BNP and NT-proBNP among physiologically and clinically relevant demographic subgroups has never been clarified in the context of the emergency department (ED). Design and methods: A blood sample taken from patients presenting to the E.D. with suspected acute coronary syndromes (ACS) was analyzed for BNP and NT-proBNP, and correlation between them was examined as an entire group then as subgroups according to gender, ethnicity, age, and comorbidity variables. Results: BNP and NT-proBNP correlate well (0.89, P < 0.0001) in a population of 420 patients and in patient subgroups with a history of various etiologies, including vascular disorders. Conclusions: In general, BNP and NT-proBNP correlate very well in patients with suspected ACS and may aid in the risk stratification process in emergency departments.",

keywords = "BNP, Chest pain, Correlation, Emergency department, NT-proBNP",

author = "Cameron, {Scott J.} and Green, {Gary B.} and White, {C. Nicole} and Laterza, {Omar F.} and William Clarke and Hong Kim and Sokoll, {Lori J.}",

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doi = "10.1016/j.clinbiochem.2005.10.011",

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journal = "Clinical Biochemistry",

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number = "1",

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T1 - Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes

AU - Cameron, Scott J.

AU - Green, Gary B.

AU - White, C. Nicole

AU - Laterza, Omar F.

AU - Clarke, William

AU - Kim, Hong

AU - Sokoll, Lori J.

PY - 2006/1

Y1 - 2006/1

N2 - Objectives: The relationship between BNP and NT-proBNP among physiologically and clinically relevant demographic subgroups has never been clarified in the context of the emergency department (ED). Design and methods: A blood sample taken from patients presenting to the E.D. with suspected acute coronary syndromes (ACS) was analyzed for BNP and NT-proBNP, and correlation between them was examined as an entire group then as subgroups according to gender, ethnicity, age, and comorbidity variables. Results: BNP and NT-proBNP correlate well (0.89, P < 0.0001) in a population of 420 patients and in patient subgroups with a history of various etiologies, including vascular disorders. Conclusions: In general, BNP and NT-proBNP correlate very well in patients with suspected ACS and may aid in the risk stratification process in emergency departments.

AB - Objectives: The relationship between BNP and NT-proBNP among physiologically and clinically relevant demographic subgroups has never been clarified in the context of the emergency department (ED). Design and methods: A blood sample taken from patients presenting to the E.D. with suspected acute coronary syndromes (ACS) was analyzed for BNP and NT-proBNP, and correlation between them was examined as an entire group then as subgroups according to gender, ethnicity, age, and comorbidity variables. Results: BNP and NT-proBNP correlate well (0.89, P < 0.0001) in a population of 420 patients and in patient subgroups with a history of various etiologies, including vascular disorders. Conclusions: In general, BNP and NT-proBNP correlate very well in patients with suspected ACS and may aid in the risk stratification process in emergency departments.

KW - BNP

KW - Chest pain

KW - Correlation

KW - Emergency department

KW - NT-proBNP

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Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes

Abstract

Keywords

ASJC Scopus subject areas

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