Assessment of Autonomic Response by Broad-Band Respiration

Ronald D. Berger, J. Philip Saul, Richard J. Cohen

Research output: Contribution to journalArticlepeer-review

96 Scopus citations


We present a technique for introducing broad-band respiratory perturbations so that the response characteristics of the autonomic nervous system can be determined noninvasively over a wide range of physiologically relevant frequencies. A subject’s respiratory bandwidth was broadened by breathing on cue to a sequence of audible tones spaced by Poisson intervals. The transfer function between the respiratory input and the resulting instantaneous heart rate was then computed using spectral analysis techniques. Results using this method are comparable to those found using traditional techniques, but are obtained with an economy of data collection.

Original languageEnglish (US)
Pages (from-to)1061-1065
Number of pages5
JournalIEEE Transactions on Biomedical Engineering
Issue number11
StatePublished - Nov 1989
Externally publishedYes

ASJC Scopus subject areas

  • Biomedical Engineering


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