Assessing the comparative effectiveness of a diagnostic technology: CT colonography

Steven D. Pearson, Amy B. Knudsen, Roberta W. Scherer, Jed Weissberg, G. Scott Gazelle

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Medical imaging is a prime example of an innovation that has brought important advances to medical care while triggering concerns about potential overuse and excessive costs. Many hopes are riding on comparative effectiveness research to help guide better decision making to improve quality and value. But the dynamic nature of medical imaging poses challenges for the traditional paradigms of evidentiary review and analysis at the heart of comparative effectiveness. This paper discusses these challenges and presents policy lessons for manufacturers, evidence reviewers, and decisionmakers, illustrated by an assessment of a prominent emerging imaging technique: computed tomography (CT) colonography.

Original languageEnglish (US)
Pages (from-to)1503-1514
Number of pages12
JournalHealth Affairs
Issue number6
StatePublished - Nov 1 2008

ASJC Scopus subject areas

  • Health Policy


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