Assessing quality of care in the diagnosis and treatment of early-stage testicular cancer: A critical review and summary

Mitchell M. Huang, Joseph G. Cheaib, Zhuo T. Su, Michael J. Biles, Ritu Sharma, Allen Zhang, Nirmish Singla, Eric B. Bass, Phillip M. Pierorazio

Research output: Contribution to journalReview articlepeer-review


Objective: To review the current literature on quality of care in the diagnosis and management of early-stage testicular cancer. Methods: PubMed, Embase, and the Cochrane Central Register of Controlled Trials were searched for studies on quality of care in testicular cancer diagnosis and management from January 1980 to August 2018. Major overlapping themes related to quality of care in the diagnosis and management of TGCT were identified and evidence related to these themes were abstracted. Evidence: 62 studies were included in the review. A number of themes were identified including (1) trends in survival and outcomes, (2) management patterns, (3) adherence to evidence-based clinical guidelines, (4) delays in care, (5) treatment complications and toxicities, (6) sociodemographic factors, (7) volume of patients treated, (8) gaps in provider knowledge and medical errors, and (9) multidisciplinary approaches to care. Evidence Summary: As survival for patients with testicular cancer improves, there has been a greater emphasis on other components of quality of care, such as reducing treatment toxicity and minimizing delays in diagnosis. Efforts to meet these goals include encouragement of adherence to evidence-based guidelines, greater utilization of surveillance, and promotion of multidisciplinary team-based care. Although outcomes have improved, social determinants of health, such as insurance status, race, and geographical residence all may influence survival and cancer-related outcomes. Additionally, qualitative review indicates patients who receive care at high-volume institutions appear to experience better outcomes than those treated at smaller centers. Conclusions: As outcomes and survival improve for patients with testicular cancer, quality of care has become an important consideration. Future avenues of research on this topic include identifying an appropriate balance between centralization of care and expanding access to underserved areas, minimizing delays in care, ensuring greater adherence to clinical guidelines, and addressing sociodemographic and racial disparities in outcomes.

Original languageEnglish (US)
Pages (from-to)400-408
Number of pages9
JournalUrologic Oncology: Seminars and Original Investigations
Issue number7
StatePublished - Jul 2021


  • Quality of Care
  • Surgical Volume
  • Survival
  • Testicular Cancer

ASJC Scopus subject areas

  • Oncology
  • Urology


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