Assemblin, a herpes virus serine maturational proteinase and new molecular target for antivirals

Wade Gibson, Anthony R. Welch, Matthew R.T. Hall

Research output: Contribution to journalArticlepeer-review

68 Scopus citations

Abstract

Herpes group viruses encode a serine proteinase that is essential for the production of infectious virus. This chapter summarizes our current understanding of its biochemical and enzymatic properties, and considers its potential as a target for antivirals.

Original languageEnglish (US)
Pages (from-to)413-426
Number of pages14
JournalPerspectives in Drug Discovery and Design
Volume2
Issue number3
DOIs
StatePublished - Jul 1995

Keywords

  • Antiviral target
  • Herpes virus
  • Serine proteinase

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

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