Aseptic necrosis of bone. An historic perspective

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13 Scopus citations


The history of aseptic bone necrosis includes important contributions by Hunter, Russell, Goodsir, Paget, Konig, Axhausen, Phemister, and Chandler. Only after Pasteur discovered bacteria in abscesses could a nonbacterial or aseptic necrosis be conceptualized. Techniques and information gained from the study of bone grafts led to important steps in the recognition of aseptic necrosis. The use of the X-ray and careful pathologic correlation enabled a wide group of radiographically distinct lesions to be recognized as bone necroses. Although many identifiable diseases can underlie aseptic necrosis, the cause of most cases is unknown.

Original languageEnglish (US)
Pages (from-to)216-221
Number of pages6
JournalClinical orthopaedics and related research
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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