Area postrema and adjacent solitary nucleus in water and energy balance

R. R. Miselis, T. M. Hyde, R. E. Shapiro

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Lesions of the area postrema (AP) and immediately adjacent nucleus tractus solitarii cause a syndrome of permanent weight loss with little disruption to behavioral controls of body weight regulation. There is also a permanent polydipsia and elevated salt appetite, which appear to be secondary to deficits in renal conservation of water and sodium. Neuroanatomical studies indicate that the immediately adjacent solitary nucleus and AP are sites of termination of visceral afferents from abdominal organs and the destination and origin of distant central afferent and efferent connections.

Original languageEnglish (US)
Pages (from-to)2969-2971
Number of pages3
JournalFederation Proceedings
Issue number15
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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