Are proteins made from a limited parts list?

Nicholas C. Fitzkee, Patrick J. Fleming, Haipeng Gong, Nicholas Panasik, Timothy O. Street, George D. Rose

Research output: Contribution to journalArticlepeer-review

65 Scopus citations


Understanding the process of protein folding has been recognized as an important challenge for >70 years. It is, quintessentially, a thermodynamic problem and, arguably, thermodynamics is our most powerful discipline for understanding biological systems. Yet, despite all this, we still lack predictive understanding of protein folding. Is something missing from this picture?

Original languageEnglish (US)
Pages (from-to)73-80
Number of pages8
JournalTrends in biochemical sciences
Issue number2
StatePublished - Feb 2005

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology


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