TY - JOUR
T1 - Application of the Impulsive Aggression Diary in Adolescents with Attention-Deficit/Hyperactivity Disorder
AU - Ceresoli-Borroni, Gianpiera
AU - Liranso, Tesfaye
AU - Brittain, Scott T.
AU - Connor, Daniel F.
AU - Evans, Christopher J.
AU - Findling, Robert L.
AU - Hwang, Steve
AU - Fry, Nicholas
AU - Candler, Shawn A.
AU - Robb, Adelaide S.
AU - Saylor, Keith E.
AU - Nasser, Azmi
AU - Schwabe, Stefan
N1 - Funding Information:
A.S.R. has received consulting fees, research support, and travel support from Actavis/Forest Laboratories and Lundbeck/Takeda and has received honoraria and travel support from AACAP, AAP, Case Western Reserve University, College of Neurologic and Psychiatric Pharmacists, Neuroscience Education Institute, Nevada Psychiatric Association, and NACCME. A.S.R. is on the data safety monitoring board for Aevi Genomic Medicine, Inc., Neu-ronetics, and NIMH. A.S.R. has received royalties from Eli Lilly, GlaxoSmithKline, Guilford Press, and Johnson and Johnson. A.S.R. has received consulting fees from Bracket and honoraria from the Child and Adolescent Psychiatric Society of Greater Washington. A.S.R. has received research support from the National Center for Advancing Translational Sciences, NINDS, Su-pernus Pharmaceuticals, Inc., and SyneuRx. A.S.R. has been an advisor for NICHD and the University of Cambridge. A.S.R. has received research support, stock/equity, and travel support from Pfizer Inc. A.S.R. has been an advisor for and received travel support from Sunovion Pharmaceuticals Inc.
Funding Information:
Funding: This study was funded by Supernus Pharmaceuticals, Inc. Editorial support was provided by IMPRINT Science, New York, New York, and was funded by Supernus Pharmaceuticals, Inc.
Funding Information:
This study was funded by Supernus Pharmaceuticals, Inc. Editorial support was provided by IMPRINT Science, New York, New York, and was funded by Supernus Pharmaceuticals, Inc.
Publisher Copyright:
© 2019, Mary Ann Liebert, Inc., publishers.
PY - 2019/10
Y1 - 2019/10
N2 - Objective: Impulsive aggression (IA) is a maladaptive form of aggressive behavior that is an associated feature of neuropsychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD). As one of the most common forms of aggressive behavior, IA is a serious clinical concern. Recognition, monitoring, and management of IA symptoms are complicated by the lack of IA-specific psychometric instruments and evidence-based treatments. A recently developed electronic observer-reported outcome instrument has been validated in children for monitoring the frequency of 15 IA-related behaviors in the context of ADHD. This study seeks to first determine if the behaviors included in the pediatric IA diary are applicable to adolescents with ADHD, and second, compare the reliability of adolescent versus parent reporters. Methods: We evaluated the utility of the pediatric IA diary through concept elicitation and cognitive interviews with 17 pairs of parents and adolescents (aged 13-17 years) with IA and ADHD, supplemented with 15 new behaviors potentially applicable to adolescents. Results: The behaviors most frequently reported by adolescents included arguing (93.8%), raising their voice/shouting/yelling (93.8%), hitting others (87.5%), slamming (87.5%), pushing/shoving (81.3%), breaking (75.0%), fighting (75.0%), throwing (75.0%), and cursing (68.8%). The behaviors most commonly reported by parents included raising their voice/shouting/yelling (94.1%), arguing (88.2%), being disrespectful/mean/rude (88.2%), slamming (88.2%), throwing (88.2%), cursing (82.4%), hitting others (82.4%), pushing/shoving (82.4%), breaking (76.5%), name-calling (76.5%), and threatening (70.6%). Of all commonly reported behaviors, only being "disrespectful/mean/rude" and "breaking" are not part of the pediatric IA diary, likely due to the imprecision of these terms. No significant usability issues were found for the IA diary device. Conclusions: These findings suggest that the 15-item pediatric IA diary should be applicable to adolescent populations to appropriately characterize IA behaviors in individuals with ADHD. Furthermore, this study indicated that parents may be more reliable reporters of IA behavior than adolescents.
AB - Objective: Impulsive aggression (IA) is a maladaptive form of aggressive behavior that is an associated feature of neuropsychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD). As one of the most common forms of aggressive behavior, IA is a serious clinical concern. Recognition, monitoring, and management of IA symptoms are complicated by the lack of IA-specific psychometric instruments and evidence-based treatments. A recently developed electronic observer-reported outcome instrument has been validated in children for monitoring the frequency of 15 IA-related behaviors in the context of ADHD. This study seeks to first determine if the behaviors included in the pediatric IA diary are applicable to adolescents with ADHD, and second, compare the reliability of adolescent versus parent reporters. Methods: We evaluated the utility of the pediatric IA diary through concept elicitation and cognitive interviews with 17 pairs of parents and adolescents (aged 13-17 years) with IA and ADHD, supplemented with 15 new behaviors potentially applicable to adolescents. Results: The behaviors most frequently reported by adolescents included arguing (93.8%), raising their voice/shouting/yelling (93.8%), hitting others (87.5%), slamming (87.5%), pushing/shoving (81.3%), breaking (75.0%), fighting (75.0%), throwing (75.0%), and cursing (68.8%). The behaviors most commonly reported by parents included raising their voice/shouting/yelling (94.1%), arguing (88.2%), being disrespectful/mean/rude (88.2%), slamming (88.2%), throwing (88.2%), cursing (82.4%), hitting others (82.4%), pushing/shoving (82.4%), breaking (76.5%), name-calling (76.5%), and threatening (70.6%). Of all commonly reported behaviors, only being "disrespectful/mean/rude" and "breaking" are not part of the pediatric IA diary, likely due to the imprecision of these terms. No significant usability issues were found for the IA diary device. Conclusions: These findings suggest that the 15-item pediatric IA diary should be applicable to adolescent populations to appropriately characterize IA behaviors in individuals with ADHD. Furthermore, this study indicated that parents may be more reliable reporters of IA behavior than adolescents.
KW - ADHD
KW - assessment tool
KW - impulsive aggression
KW - maladaptive aggression
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U2 - 10.1089/cap.2018.0089
DO - 10.1089/cap.2018.0089
M3 - Article
C2 - 31343272
AN - SCOPUS:85072993885
SN - 1044-5463
VL - 29
SP - 599
EP - 607
JO - Journal of child and adolescent psychopharmacology
JF - Journal of child and adolescent psychopharmacology
IS - 8
ER -