TY - JOUR
T1 - Application of the directed transfer function method to mesial and lateral onset temporal lobe seizures
AU - Franaszczuk, Piotr J.
AU - Bergey, Gregory K.
N1 - Funding Information:
* Maryland Epilepsy Center, Baltimore, MD, USA. ^ Department ofNeurology, Baltimore,MD,USA. + Department of Physiology, University of Maryland School of Medicine and MedicalCenter,Baltimore,MD,USA. Accepted for publication: April 21,1998. We would like to thank C.P. Fleming, R.EEG.T. for her assistance in obtaining and processing the EEG recordings. Our colleagues at the Maryland Epilepsy Center, Drs. S. Alemayehu, E. Barry, H. Eisenberg, A. Krumholz, F. Mwaisela and A. Wolf participated in the care of these patients. This study was supported by NIH grant NS 33732-01. Correspondence and reprint requests should be addressed to Piotr J. Franaszczuk, Ph.D., Maryland Epilepsy Center, Department of Neurology, University ofMarylandSchool ofMedicine and MedicalCenter, 22 South Greene Street, Baltimore,MD, 21201USA. Fax: 410-706-0186 email: [email protected] Copyright © 1998 Human Sciences Press, Inc.
PY - 1998
Y1 - 1998
N2 - The directed transfer function (DTF) method is a multichannel analysis based on an autoregressive model that detects flow of seizure activity. This report extends the application of the DTF method to compare patterns of flow of seizures with different sites of origin. Analysis of a seizure originating from mesial temporal structures is compared with a seizure originating from lateral temporal neocortex; both complex partial seizures were recorded with intracranial electrodes that combine subdural grid arrays and depth electrodes. The DTF method has the potential to determine patterns of flow of activity, including periods when visual analysis of the intracranial ictal EEG may not allow for definitive source localization. The extension of the DTF analyses into integrated DTF (IDTF) formats is also illustrated. When activity of a relatively discrete frequency can be identified, the IDTF analysis facilitates display of patterns of flow of this selected activity.
AB - The directed transfer function (DTF) method is a multichannel analysis based on an autoregressive model that detects flow of seizure activity. This report extends the application of the DTF method to compare patterns of flow of seizures with different sites of origin. Analysis of a seizure originating from mesial temporal structures is compared with a seizure originating from lateral temporal neocortex; both complex partial seizures were recorded with intracranial electrodes that combine subdural grid arrays and depth electrodes. The DTF method has the potential to determine patterns of flow of activity, including periods when visual analysis of the intracranial ictal EEG may not allow for definitive source localization. The extension of the DTF analyses into integrated DTF (IDTF) formats is also illustrated. When activity of a relatively discrete frequency can be identified, the IDTF analysis facilitates display of patterns of flow of this selected activity.
KW - Autoregressive model
KW - Complex partial seizure
KW - Directed transfer function
KW - Propagation
KW - Temporal lobe
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U2 - 10.1023/A:1022262318579
DO - 10.1023/A:1022262318579
M3 - Article
C2 - 9758388
AN - SCOPUS:0031692073
SN - 0896-0267
VL - 11
SP - 13
EP - 21
JO - Brain Topography
JF - Brain Topography
IS - 1
ER -